Abcb5 ATP binding cassette subfamily B member 5 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Abcb5provided by RGD
Official Full Name: ATP binding cassette subfamily B member 5provided by RGD
Primary source: RGD:1566342
See related: EnsemblRapid:ENSRNOG00000006398 AllianceGenome:RGD:1566342
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1566342
Summary: Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Predicted to be involved in eye development; regulation of membrane potential; and transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in apical plasma membrane. Orthologous to human ABCB5 (ATP binding cassette subfamily B member 5). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in Testes (RPKM 1.2) and Liver (RPKM 0.0) See more
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (145978860..146075776, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (139836528..139932830, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (146805481..146902339, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Expression of the Stem Cell Marker ABCB5 in Normal and Tumor Tissues.
Title: Expression of the Stem Cell Marker ABCB5 in Normal and Tumor Tissues.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables efflux transmembrane transporter activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in eye development	ISO Inferred from Sequence Orthology more info
involved_in regulation of membrane potential	ISO Inferred from Sequence Orthology more info
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in apical plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

Names: ATP-binding cassette, sub-family B (MDR/TAP), member 5; ATP-binding cassette, subfamily B (MDR/TAP), member 5

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The following sections contain reference sequences that belong to a specific genome build. Explain