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    Golga3 golgin A3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 312077, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Golga3provided by RGD
    Official Full Name
    golgin A3provided by RGD
    Primary source
    RGD:1305262
    See related
    EnsemblRapid:ENSRNOG00000037437 AllianceGenome:RGD:1305262
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in several cellular components, including Golgi membrane; endoplasmic reticulum-Golgi intermediate compartment; and nuclear lumen. Orthologous to human GOLGA3 (golgin A3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 77.7), Kidney (RPKM 73.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Golga3 in Genome Data Viewer
    Location:
    12q16
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (52112129..52160311, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (46452409..46500509, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (52510509..52558606, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene PGAM family member 5, mitochondrial serine/threonine protein phosphatase Neighboring gene ankyrin repeat and LEM domain containing 2 Neighboring gene uncharacterized LOC134481217 Neighboring gene checkpoint with forkhead and ring finger domains Neighboring gene zinc finger protein 605 Neighboring gene GTP binding protein 6 (putative)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of GCP16, a novel acylated Golgi protein that interacts with GCP170. Ohta E, et al. J Biol Chem, 2003 Dec 19. PMID 14522980
    2. Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex. Fritzler MJ, et al. J Exp Med, 1993 Jul 1. PMID 8315394, Free PMC Article
    3. Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X. Bray JD, et al. Genomics, 2002 Jun. PMID 12036294
    4. Proteomics characterization of abundant Golgi membrane proteins. Bell AW, et al. J Biol Chem, 2001 Feb 16. PMID 11042173
    5. E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Guo Z, et al. Sci Signal, 2014 Dec 2. PMID 25468996, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    golgin subfamily A member 3
    Names
    Golgin subfamily A member 3
    golgi autoantigen, golgin subfamily a, 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107847.1 → NP_001101317.1  golgin subfamily A member 3

      See identical proteins and their annotated locations for NP_001101317.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473973
      UniProtKB/TrEMBL
      A0A0G2K5A4, A6J2C3
      Conserved Domains (2) summary
      pfam01576
      Location:353 → 1339
      Myosin_tail_1; Myosin tail
      cl19872
      Location:561 → 854
      DUF885; Bacterial protein of unknown function (DUF885)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      52112129..52160311 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271404.1 → XP_063127474.1  golgin subfamily A member 3 isoform X2

    2. XM_006249563.5 → XP_006249625.1  golgin subfamily A member 3 isoform X1

      See identical proteins and their annotated locations for XP_006249625.1

      UniProtKB/TrEMBL
      A0A0G2K5A4, A6J2C4, D3ZLD5
      Related
      ENSRNOP00000053494.3, ENSRNOT00000056656.4
      Conserved Domains (1) summary
      TIGR02168
      Location:663 → 1351
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. XM_039089528.2 → XP_038945456.1  golgin subfamily A member 3 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K5A4, A6J2C4, D3ZLD5
      Conserved Domains (1) summary
      TIGR02168
      Location:663 → 1351
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    4. XM_063271406.1 → XP_063127476.1  golgin subfamily A member 3 isoform X4

      UniProtKB/TrEMBL
      A6J2C3

    5. XM_039089529.2 → XP_038945457.1  golgin subfamily A member 3 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K5A4, A6J2C4, D3ZLD5
      Conserved Domains (1) summary
      TIGR02168
      Location:663 → 1351
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    6. XM_063271407.1 → XP_063127477.1  golgin subfamily A member 3 isoform X5

    7. XM_063271405.1 → XP_063127475.1  golgin subfamily A member 3 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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