Zswim6 zinc finger, SWIM-type containing 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zswim6provided by RGD
Official Full Name: zinc finger, SWIM-type containing 6provided by RGD
Primary source: RGD:1306624
See related: EnsemblRapid:ENSRNOG00000014528 AllianceGenome:RGD:1306624
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ab2-064
Summary: Predicted to be involved in striatal medium spiny neuron differentiation. Predicted to act upstream of or within neuron projection morphogenesis and regulation of neuron migration. Predicted to be located in stereocilium. Predicted to be part of Cul2-RING ubiquitin ligase complex. Human ortholog(s) of this gene implicated in acromelic frontonasal dysostosis. Orthologous to human ZSWIM6 (zinc finger SWIM-type containing 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Lung (RPKM 68.9), Spleen (RPKM 53.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q14

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (40944617..41112340, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (39211131..39378877, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (38978042..39042886, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BI285441 (e-PCR)
- UniSTS:244781

D2Got22 (e-PCR)
- UniSTS:115761

RH144303 (e-PCR)
- UniSTS:233548

D2Got18 (e-PCR)
- UniSTS:112210

AI008171 (e-PCR)
- UniSTS:250465

BM387016 (e-PCR)
- UniSTS:261236

RH130599 (e-PCR)
- UniSTS:213883

D2Rat12 (e-PCR)
- UniSTS:118661

BF397496 (e-PCR)
- UniSTS:246192

AU048211 (e-PCR)
- UniSTS:109761

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within neuron projection morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of neuron migration	ISO Inferred from Sequence Orthology more info
involved_in striatal medium spiny neuron differentiation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of Cul2-RING ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in stereocilium	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc finger SWIM domain-containing protein 6

Names: zinc finger, SWIM domain containing 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001433121.1 → NP_001420050.1 zinc finger SWIM domain-containing protein 6 isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000002
NM_001433122.1 → NP_001420051.1 zinc finger SWIM domain-containing protein 6 isoform 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000002

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086020.1 Reference GRCr8

Range

40944617..41112340 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039103499.2 → XP_038959427.2 zinc finger SWIM domain-containing protein 6 isoform X1

Related

ENSRNOP00000059251.4, ENSRNOT00000064292.5
XM_063282687.1 → XP_063138757.1 zinc finger SWIM domain-containing protein 6 isoform X2

UniProtKB/TrEMBL

A6I5J1
XM_063282688.1 → XP_063138758.1 zinc finger SWIM domain-containing protein 6 isoform X3

UniProtKB/TrEMBL

F1M5P6

RNA

XR_010063737.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001047884.1: Suppressed sequence

Description

NM_001047884.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from mouse, laboratory: Zswim6 (GeneID:67263).