Ogfod3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ogfod3provided by RGD
Official Full Name: 2-oxoglutarate and iron-dependent oxygenase domain containing 3provided by RGD
Primary source: RGD:1305007
See related: EnsemblRapid:ENSRNOG00000036668 AllianceGenome:RGD:1305007
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1305007
Summary: Predicted to enable several functions, including L-ascorbic acid binding activity; dioxygenase activity; and iron ion binding activity. Predicted to be located in membrane. Orthologous to human OGFOD3 (2-oxoglutarate and iron dependent oxygenase domain containing 3). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in Kidney (RPKM 102.0), Liver (RPKM 61.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q32.3

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (106950640..106978422, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (106452334..106480632, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (110378533..110406377, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables L-ascorbic acid binding	IEA Inferred from Electronic Annotation more info
enables dioxygenase activity	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

Names: PKHD domain-containing transmembrane protein C17orf101 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013976.1 → NP_001013998.1 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

See identical proteins and their annotated locations for NP_001013998.1

Status: PROVISIONAL

Source sequence(s)

BC088238

UniProtKB/Swiss-Prot

Q5M843

UniProtKB/TrEMBL

A0A8I6GJA4, A6HLM9

Related

ENSRNOP00000051808.3, ENSRNOT00000054925.4

Conserved Domains (1) summary

smart00702
Location:158 → 302

P4Hc; Prolyl 4-hydroxylase alpha subunit homologues