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    Mmgt2 membrane magnesium transporter 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303211, updated on 14-Nov-2024

    Summary

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    Official Symbol
    Mmgt2provided by RGD
    Official Full Name
    membrane magnesium transporter 2provided by RGD
    Primary source
    RGD:1311260
    See related
    EnsemblRapid:ENSRNOG00000069117 AllianceGenome:RGD:1311260
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311260
    Summary
    Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in magnesium ion transport. Predicted to be located in Golgi membrane and early endosome membrane. Predicted to be part of EMC complex. Predicted to be active in Golgi apparatus; early endosome; and plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 46.7), Heart (RPKM 40.1) and 9 other tissues See more
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    Genomic context

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    See Mmgt2 in Genome Data Viewer
    Location:
    10q23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (47842722..47859787)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (47343446..47362889)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (48986163..48989596)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel, subfamily V, member 2 Neighboring gene small nucleolar RNA, C/D box 65 Neighboring gene leucine rich repeat containing 75A Neighboring gene uncharacterized LOC120095115 Neighboring gene zinc finger protein 287 Neighboring gene transfer RNA tryptophan (anticodon CCA) 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cobalt ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables copper ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inorganic cation transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables magnesium ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables manganese ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nickel cation transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cobalt ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in copper ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in magnesium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in magnesium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in manganese ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nickel cation transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of EMC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of EMC complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in early endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in early endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    membrane magnesium transporter 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013967.2 → NP_001013989.2  membrane magnesium transporter 2

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      Q6P719
      UniProtKB/TrEMBL
      A0A8I6A4V9, A6HFB7
      Related
      ENSRNOP00000085801.1, ENSRNOT00000102374.2
      Conserved Domains (1) summary
      pfam10270
      Location:29 → 90
      MMgT; Membrane magnesium transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      47842722..47859787
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039085969.2 → XP_038941897.1  membrane magnesium transporter 2 isoform X1

      UniProtKB/Swiss-Prot
      Q6P719
      UniProtKB/TrEMBL
      A0A8I6A4V9, A6HFB7
      Related
      ENSRNOP00000092726.1, ENSRNOT00000118425.2
      Conserved Domains (1) summary
      pfam10270
      Location:29 → 90
      MMgT; Membrane magnesium transporter

    2. XM_039085971.2 → XP_038941899.1  membrane magnesium transporter 2 isoform X1

      UniProtKB/Swiss-Prot
      Q6P719
      UniProtKB/TrEMBL
      A0A8I6A4V9, A6HFB7
      Related
      ENSRNOP00000081126.1, ENSRNOT00000107468.2
      Conserved Domains (1) summary
      pfam10270
      Location:29 → 90
      MMgT; Membrane magnesium transporter
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P719.1 GenPept UniProtKB/Swiss-Prot:Q6P719

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials