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    Mrps35 mitochondrial ribosomal protein S35 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297727, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Mrps35provided by RGD
    Official Full Name
    mitochondrial ribosomal protein S35provided by RGD
    Primary source
    RGD:1306720
    See related
    EnsemblRapid:ENSRNOG00000001842 AllianceGenome:RGD:1306720
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Orthologous to human MRPS35 (mitochondrial ribosomal protein S35). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 132.3), Kidney (RPKM 95.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mrps35 in Genome Data Viewer
    Location:
    4q44
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (181688715..181719403)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (179958067..179988752)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (181434793..181465318)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene PPFIA binding protein 1 Neighboring gene high mobility group protein B1-like Neighboring gene RAB15 effector protein Neighboring gene MANSC domain containing 4 Neighboring gene kelch-like family, member 42 Neighboring gene uncharacterized LOC134486873

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth. Mertz J, et al. Mol Cell Proteomics, 2015 Jul. PMID 25931508, Free PMC Article
    2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    3. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    4. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small ribosomal subunit protein mS35
    Names
    28S ribosomal protein S35, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106628.3 → NP_001100098.1  small ribosomal subunit protein mS35

      See identical proteins and their annotated locations for NP_001100098.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A6IN39, D4A9Z6
      Conserved Domains (1) summary
      cl40670
      Location:162 → 230
      PCRF; PCRF domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      181688715..181719403
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039107482.2 → XP_038963410.1  small ribosomal subunit protein mS35 isoform X5

      Conserved Domains (1) summary
      cl40670
      Location:162 → 208
      PCRF; PCRF domain

    2. XM_006237676.4 → XP_006237738.1  small ribosomal subunit protein mS35 isoform X1

      Related
      ENSRNOP00000110763.1, ENSRNOT00000170282.1
      Conserved Domains (1) summary
      pfam10213
      Location:160 → 228
      MRP-S28; Mitochondrial ribosomal subunit protein

    3. XM_006237677.3 → XP_006237739.1  small ribosomal subunit protein mS35 isoform X3

    4. XM_063285921.1 → XP_063141991.1  small ribosomal subunit protein mS35 isoform X6

    5. XM_063285920.1 → XP_063141990.1  small ribosomal subunit protein mS35 isoform X4

    6. XM_039107483.2 → XP_038963411.1  small ribosomal subunit protein mS35 isoform X7

    7. XM_017592600.2 → XP_017448089.1  small ribosomal subunit protein mS35 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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