Lgals12 galectin 12 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lgals12provided by RGD
Official Full Name: galectin 12provided by RGD
Primary source: RGD:1306914
See related: EnsemblRapid:ENSRNOG00000021207 AllianceGenome:RGD:1306914
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable integrin binding activity and lactose binding activity. Predicted to be involved in intrinsic apoptotic signaling pathway and lymphatic endothelial cell migration. Predicted to be located in mitochondrion and nucleus. Predicted to be active in cytoplasm. Orthologous to human LGALS12 (galectin 12). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Adrenal (RPKM 19.5), Thymus (RPKM 15.1) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q43

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (214261216..214272825, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (204832065..204842759, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (222891626..222903728, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH139878 (e-PCR)
- UniSTS:221962

AU049108 (e-PCR)
- UniSTS:145556

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables lactose binding	IBA Inferred from Biological aspect of Ancestor more info
enables lactose binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in intrinsic apoptotic signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intrinsic apoptotic signaling pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: galectin-12

Names: lectin, galactose binding, soluble 12; lectin, galactoside-binding, soluble, 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.