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    Snrpd1 small nuclear ribonucleoprotein D1 polypeptide [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291794, updated on 18-Sep-2024

    Summary

    Official Symbol
    Snrpd1provided by RGD
    Official Full Name
    small nuclear ribonucleoprotein D1 polypeptideprovided by RGD
    Primary source
    RGD:1306345
    See related
    EnsemblRapid:ENSRNOG00000013714 AllianceGenome:RGD:1306345
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables U1 snRNP binding activity. Predicted to be involved in spliceosomal snRNP assembly. Located in nucleus. Part of U1 snRNP. Used to study nephritis; proteinuria; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in connective tissue disease; nephritis; proteinuria; and systemic lupus erythematosus. Orthologous to human SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 273.6), Brain (RPKM 178.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Snrpd1 in Genome Data Viewer
    Location:
    18p13
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (1969351..1980207)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (1696838..1707400)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (1866066..1876613)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 1 Neighboring gene ATP synthase membrane subunit G like 4 Neighboring gene uncharacterized LOC134482900 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene abhydrolase domain containing 3, phospholipase Neighboring gene histidine-rich glycoprotein-like Neighboring gene MIB E3 ubiquitin protein ligase 1 Neighboring gene small nucleolar RNA SNORA70

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables U1 snRNP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spliceosomal snRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spliceosomal snRNP assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of SMN-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SMN-Sm protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U1 snRNP IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of U1 snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U12-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U4 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U4 snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U4/U6 x U5 tri-snRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of commitment complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of methylosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of pICln-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of pICln-Sm protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    small nuclear ribonucleoprotein Sm D1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106163.1NP_001099633.1  small nuclear ribonucleoprotein Sm D1

      See identical proteins and their annotated locations for NP_001099633.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474073
      UniProtKB/TrEMBL
      A6KNE7, B2RZB7, F7F176
      Related
      ENSRNOP00000018646.4, ENSRNOT00000018646.7
      Conserved Domains (1) summary
      cd01724
      Location:293
      Sm_D1; Sm protein D1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      1969351..1980207
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008771943.4XP_008770165.1  small nuclear ribonucleoprotein Sm D1 isoform X1

      See identical proteins and their annotated locations for XP_008770165.1

      Conserved Domains (1) summary
      cl00259
      Location:252
      Sm_like; Sm and related proteins