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    NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 [ Bos taurus (domestic cattle) ]

    Gene ID: 287327, updated on 10-Oct-2024

    Summary

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    Official Symbol
    NDUFS3provided by VGNC
    Official Full Name
    NADH:ubiquinone oxidoreductase core subunit S3provided by VGNC
    Primary source
    VGNC:VGNC:50228
    See related
    BGD:BT15899; Ensembl:ENSBTAG00000018483
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See NDUFS3 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (77378793..77383890)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene CUGBP Elav-like family member 1 Neighboring gene protein tyrosine phosphatase mitochondrial 1 Neighboring gene kelch repeat and BTB domain containing 4 Neighboring gene family with sequence similarity 180 member B Neighboring gene C1q and TNF related 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The 30-kilodalton subunit of bovine mitochondrial complex I is homologous to a protein coded in chloroplast DNA. Pilkington SJ, et al. Biochemistry, 1991 Feb 19. PMID 1899621
    2. The amino acid sequences of two 13 kDa polypeptides and partial amino acid sequence of 30 kDa polypeptide of complex I from bovine heart mitochondria: possible location of iron-sulfur clusters. Masui R, et al. J Biochem, 1991 Apr. PMID 1907966
    3. Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits. Carroll J, et al. J Biol Chem, 2002 Dec 27. PMID 12381726
    4. Architecture of mammalian respiratory complex I. Vinothkumar KR, et al. Nature, 2014 Nov 6. PMID 25209663, Free PMC Article
    5. Resolution of the membrane domain of bovine complex I into subcomplexes: implications for the structural organization of the enzyme. Sazanov LA, et al. Biochemistry, 2000 Jun 20. PMID 10852722

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. subunits of complex I and two subcomplexes (Ialpha and Ibeta) were resolved on one- and two-dimensional gels and by reverse-phase high performance liquid chromatography
      Title: Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NADH dehydrogenase (ubiquinone) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Names
    CI-30kD
    NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
    NADH-ubiquinone oxidoreductase 30 kDa subunit
    complex I-30kD
    NP_777244.1
    XP_059730562.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174819.3 → NP_777244.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor

      See identical proteins and their annotated locations for NP_777244.1

      Status: PROVISIONAL

      Source sequence(s)
      M58469
      UniProtKB/TrEMBL
      F1MS25
      Related
      ENSBTAP00000024600.5, ENSBTAT00000024600.5
      Conserved Domains (1) summary
      PRK06074
      Location:60 → 242
      PRK06074; NADH dehydrogenase subunit C; Provisional

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      77378793..77383890
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059874579.1 → XP_059730562.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P23709.1 GenPept UniProtKB/Swiss-Prot:P23709

    Gene LinkOut

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