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    SDHB succinate dehydrogenase complex iron sulfur subunit B [ Bos taurus (domestic cattle) ]

    Gene ID: 286840, updated on 4-Oct-2024

    Summary

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    Official Symbol
    SDHBprovided by VGNC
    Official Full Name
    succinate dehydrogenase complex iron sulfur subunit Bprovided by VGNC
    Primary source
    VGNC:VGNC:34391
    See related
    BGD:BT27935; Ensembl:ENSBTAG00000008314
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SDHB in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (135549091..135578116)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene peptidyl arginine deiminase 1 Neighboring gene peptidyl arginine deiminase 2 Neighboring gene ATPase cation transporting 13A2 Neighboring gene microfibril associated protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Forms of selenium in vitamin-mineral mixes differentially affect the expression of genes responsible for prolactin, ACTH, and α-MSH synthesis and mitochondrial dysfunction in pituitaries of steers grazing endophyte-infected tall fescue. Li Q, et al. J Anim Sci, 2019 Feb 1. PMID 30476104, Free PMC Article
    2. Housekeeping genes for phylogenetic analysis of eutherian relationships. Kullberg M, et al. Mol Biol Evol, 2006 Aug. PMID 16751257
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC127046

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in aerobic respiration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in respiratory electron transport chain IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
    Names
    IP
    iron-sulfur subunit of complex II
    malate dehydrogenase [quinone] iron-sulfur subunit
    succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
    NP_001035573.1
    XP_015315535.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040483.2 → NP_001035573.1  succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001035573.1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002
      UniProtKB/Swiss-Prot
      Q3T189
      UniProtKB/TrEMBL
      Q0QEX9
      Related
      ENSBTAP00000010949.5, ENSBTAT00000010949.5
      Conserved Domains (3) summary
      PLN00129
      Location:1 → 271
      PLN00129; succinate dehydrogenase [ubiquinone] iron-sulfur subunit
      pfam13085
      Location:41 → 147
      Fer2_3; 2Fe-2S iron-sulfur cluster binding domain
      pfam13534
      Location:185 → 258
      Fer4_17; 4Fe-4S dicluster domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      135549091..135578116
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015460049.1 → XP_015315535.1  succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial isoform X1

      UniProtKB/TrEMBL
      Q0QEX9
      Conserved Domains (3) summary
      PRK05950
      Location:23 → 254
      sdhB; succinate dehydrogenase iron-sulfur subunit; Reviewed
      pfam13085
      Location:23 → 129
      Fer2_3; 2Fe-2S iron-sulfur cluster binding domain
      pfam13534
      Location:167 → 240
      Fer4_17; 4Fe-4S dicluster domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3T189.1 GenPept UniProtKB/Swiss-Prot:Q3T189

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials