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    PAOX polyamine oxidase [ Bos taurus (domestic cattle) ]

    Gene ID: 282639, updated on 4-Oct-2024

    Summary

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    Official Symbol
    PAOXprovided by VGNC
    Official Full Name
    polyamine oxidaseprovided by VGNC
    Primary source
    VGNC:VGNC:32570
    See related
    Ensembl:ENSBTAG00000018321
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PAOX in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (25602015..25629449, complement)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene sortilin related VPS10 domain containing receptor 3 Neighboring gene scavenger receptor cysteine-rich domain-containing protein SCART1 Neighboring gene olfactory receptor family 6 subfamily AE member 1 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene shadow of prion protein Neighboring gene mitochondrial ribosome associated GTPase 1 Neighboring gene enoyl-CoA hydratase, short chain 1 Neighboring gene fucose mutarotase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning, sequencing, and heterologous expression of the murine peroxisomal flavoprotein, N1-acetylated polyamine oxidase. Wu T, et al. J Biol Chem, 2003 Jun 6. PMID 12660232
    2. Cloning of the bovine prion-like Shadoo (SPRN) gene by comparative analysis of the predicted genomic locus. Uboldi C, et al. Mamm Genome, 2006 Nov. PMID 17091316
    3. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    4. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables polyamine oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxisomal N(1)-acetyl-spermine/spermidine oxidase
    Names
    peroxisomal N1-acetyl-spermine/spermidine oxidase
    NP_001013620.2
    XP_005225507.2
    XP_005225508.2
    XP_010818099.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013602.2 → NP_001013620.2  peroxisomal N(1)-acetyl-spermine/spermidine oxidase

      See identical proteins and their annotated locations for NP_001013620.2

      Status: PROVISIONAL

      Source sequence(s)
      DQ058607
      UniProtKB/Swiss-Prot
      Q4PS79, Q865R1
      UniProtKB/TrEMBL
      A4IFI4
      Related
      ENSBTAP00000048799.3, ENSBTAT00000057083.3
      Conserved Domains (2) summary
      PLN02568
      Location:15 → 498
      PLN02568; polyamine oxidase
      pfam13450
      Location:44 → 88
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      25602015..25629449 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005225451.4 → XP_005225508.2  peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform X3

      UniProtKB/TrEMBL
      A0AAA9SBP6, A0AAA9TBR3
      Related
      ENSBTAP00000094122.1, ENSBTAT00000132748.1
      Conserved Domains (1) summary
      cl27535
      Location:155 → 638
      Amino_oxidase; Flavin containing amine oxidoreductase

    2. XM_010819797.4 → XP_010818099.2  peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform X1

      UniProtKB/TrEMBL
      A0AAA9SBP6
      Conserved Domains (1) summary
      cl27535
      Location:155 → 609
      Amino_oxidase; Flavin containing amine oxidoreductase

    3. XM_005225450.5 → XP_005225507.2  peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform X2

      UniProtKB/TrEMBL
      A0AAA9SBP6
      Conserved Domains (1) summary
      cl27535
      Location:155 → 639
      Amino_oxidase; Flavin containing amine oxidoreductase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q865R1.3 GenPept UniProtKB/Swiss-Prot:Q865R1

    Gene LinkOut

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    Research Materials