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    TYRP1 tyrosinase related protein 1 [ Bos taurus (cattle) ]

    Gene ID: 282105, updated on 5-Mar-2024

    Summary

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    Official Symbol
    TYRP1provided by VGNC
    Official Full Name
    tyrosinase related protein 1provided by VGNC
    Primary source
    VGNC:VGNC:36553
    See related
    BGD:BT11287; Ensembl:ENSBTAG00000020985
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TYRP1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (31632079..31648318, complement)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene calponin-3-like Neighboring gene leucine rich adaptor protein 1 like Neighboring gene tropomyosin alpha-4 chain-like Neighboring gene large ribosomal subunit protein uL3-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TYRP1 is associated with dun coat colour in Dexter cattle or how now brown cow? Berryere TG, et al. Anim Genet, 2003 Jun. PMID 12755816
    2. Molecular variation in pigmentation genes contributing to coat colour in native Korean Hanwoo cattle. Mohanty TR, et al. Anim Genet, 2008 Oct. PMID 18557975
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in melanocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in melanosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in melanosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5,6-dihydroxyindole-2-carboxylic acid oxidase
    Names
    DHICA oxidase
    TRP-1
    TRP1
    NP_776905.2
    XP_015327929.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174480.3 → NP_776905.2  5,6-dihydroxyindole-2-carboxylic acid oxidase precursor

      See identical proteins and their annotated locations for NP_776905.2

      Status: PROVISIONAL

      Source sequence(s)
      AF445638
      UniProtKB/Swiss-Prot
      Q8WN57
      UniProtKB/TrEMBL
      Q95JD8
      Related
      ENSBTAP00000027945.6, ENSBTAT00000027945.6
      Conserved Domains (1) summary
      pfam00264
      Location:183 → 417
      Tyrosinase; Common central domain of tyrosinase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      31632079..31648318 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015472443.3 → XP_015327929.2  5,6-dihydroxyindole-2-carboxylic acid oxidase isoform X1

      UniProtKB/TrEMBL
      F1MBG9, Q95JD8
      Conserved Domains (1) summary
      pfam00264
      Location:183 → 417
      Tyrosinase; Common central domain of tyrosinase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WN57.2 GenPept UniProtKB/Swiss-Prot:Q8WN57

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials