FTH1 ferritin heavy chain 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: FTH1provided by VGNC
Official Full Name: ferritin heavy chain 1provided by VGNC
Primary source: VGNC:VGNC:56265
See related: BGD:BT26964; Ensembl:ENSBTAG00000011184
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: FTH
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 29

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	29	NC_037356.1 (40477532..40480196, complement)

Chromosome 29 - NC_037356.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Ferritin-dependent cellular autophagy pathway promotes ferroptosis in beef during cold storage.
Title: Ferritin-dependent cellular autophagy pathway promotes ferroptosis in beef during cold storage.
ferritin heavy chain up-regulation may be mediated by activation of NF-kappaB and that in turn this may be related to the resistance of bovine papillomavirus type-2 (BPV-2) infected urothelial cells to apoptosis.
Title: Ferritin heavy chain (FHC) is up-regulated in papillomavirus-associated urothelial tumours of the urinary bladder in cattle.

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General gene information

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Markers

IGFBP6 (e-PCR)
- UniSTS:278560

RH94403 (e-PCR)
- UniSTS:119651

MARC_4179-4180:991938416:1 (e-PCR)
- UniSTS:231076

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ferric iron binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ferrous iron binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular iron ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular sequestering of iron ion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in iron ion transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ferritin heavy chain

Names: ferritin H subunit; ferritin protein

NP_776487.1

EC 1.16.3.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.