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    ACP1 acid phosphatase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 280977, updated on 4-Oct-2024

    Summary

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    Official Symbol
    ACP1provided by VGNC
    Official Full Name
    acid phosphatase 1provided by VGNC
    Primary source
    VGNC:VGNC:59193
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See ACP1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (112748914..112763271, complement)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101903368 Neighboring gene uncharacterized LOC132346028 Neighboring gene ALK and LTK ligand 2 Neighboring gene SH3 and SYLF domain containing 1 Neighboring gene family with sequence similarity 110 member C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of bovine low molecular weight phosphotyrosyl phosphatase complexed with the transition state analog vanadate. Zhang M, et al. Biochemistry, 1997 Jan 7. PMID 8993313
    2. The role of Cys12, Cys17 and Arg18 in the catalytic mechanism of low-M(r) cytosolic phosphotyrosine protein phosphatase. Cirri P, et al. Eur J Biochem, 1993 Jun 15. PMID 8319676
    3. Backbone 1H, 13C, and 15N assignments and secondary structure of bovine low molecular weight phosphotyrosyl protein phosphatase. Zhou MM, et al. Biochemistry, 1994 May 3. PMID 8172896
    4. The role of His66 and His72 in the reaction mechanism of bovine liver low-M(r) phosphotyrosine protein phosphatase. Chiarugi P, et al. Biochem J, 1994 Mar 1. PMID 8135752, Free PMC Article
    5. Kinetic and site-directed mutagenesis studies of the cysteine residues of bovine low molecular weight phosphotyrosyl protein phosphatase. Davis JP, et al. J Biol Chem, 1994 Mar 25. PMID 8132604

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC128334

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acid phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    low molecular weight phosphotyrosine protein phosphatase
    Names
    LMW-PTP
    LMW-PTPase
    acid phosphatase 1, soluble
    low molecular weight cytosolic acid phosphatase
    phosphatase 1, soluble
    ptpase
    NP_776403.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173978.2 → NP_776403.1  low molecular weight phosphotyrosine protein phosphatase

      See identical proteins and their annotated locations for NP_776403.1

      Status: PROVISIONAL

      Source sequence(s)
      M83656
      UniProtKB/Swiss-Prot
      P11064
      Conserved Domains (1) summary
      cd00115
      Location:7 → 155
      LMWPc; Low molecular weight phosphatase family;

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      112748914..112763271 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P11064.3 GenPept UniProtKB/Swiss-Prot:P11064

    Gene LinkOut

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