U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CNP 2',3'-cyclic nucleotide 3' phosphodiesterase [ Bos taurus (domestic cattle) ]

    Gene ID: 280752, updated on 4-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CNPprovided by VGNC
    Official Full Name
    2',3'-cyclic nucleotide 3' phosphodiesteraseprovided by VGNC
    Primary source
    VGNC:VGNC:27525
    See related
    Ensembl:ENSBTAG00000025762
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CNP in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (42130977..42138137)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene ATP citrate lyase Neighboring gene outer dynein arm docking complex subunit 4 Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene NFKB inhibitor interacting Ras like 2 Neighboring gene zinc finger protein 385C

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Chemical, immunological and catalytic properties of 2':3'-cyclic nucleotide 3'-phosphodiesterase purified from brain white matter. Kurihara T, et al. Biochem J, 1981 Apr 1. PMID 6272743, Free PMC Article
    2. Molecular cloning of the myelin specific enzyme 2',3'-cyclic-nucleotide 3'-phosphohydrolase. Vogel US, et al. FEBS Lett, 1987 Jun 29. PMID 3036592
    3. cDNA cloning and amino acid sequence of bovine brain 2',3'-cyclic-nucleotide 3'-phosphodiesterase. Kurihara T, et al. J Biol Chem, 1987 Mar 5. PMID 3029107
    4. Nucleotide sequence of bovine retina 2',3'-cyclic nucleotide 3'-phosphohydrolase. Vogel US, et al. Nucleic Acids Res, 1987 Sep 11. PMID 2821502, Free PMC Article
    5. Analysis of the interacting partners of the neuronal calcium-binding proteins L-CaBP1, hippocalcin, NCS-1 and neurocalcin delta. Haynes LP, et al. Proteomics, 2006 Mar. PMID 16470652

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cyclic nucleotide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    2',3'-cyclic-nucleotide 3'-phosphodiesterase
    Names
    CNPase
    elastase 2',3'-cyclic-nucleotide 3'-phosphodiesterase
    NP_851336.1
    XP_005220718.1
    XP_005220719.1
    XP_010814515.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_180993.2 → NP_851336.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase

      See identical proteins and their annotated locations for NP_851336.1

      Status: PROVISIONAL

      Source sequence(s)
      J02659
      UniProtKB/Swiss-Prot
      P06623
      Conserved Domains (2) summary
      pfam05881
      Location:166 → 378
      CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
      cl17190
      Location:31 → 145
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      42130977..42138137
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220661.3 → XP_005220718.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X1

      UniProtKB/TrEMBL
      A0AAA9TS26
      Related
      ENSBTAP00000100133.1, ENSBTAT00000108548.1
      Conserved Domains (2) summary
      pfam05881
      Location:186 → 398
      CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
      cl26098
      Location:52 → 165
      AAA_33; AAA domain

    2. XM_005220662.4 → XP_005220719.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X2

      See identical proteins and their annotated locations for XP_005220719.1

      UniProtKB/Swiss-Prot
      P06623, Q3SZJ6
      Related
      ENSBTAP00000036278.2, ENSBTAT00000036420.4
      Conserved Domains (2) summary
      pfam05881
      Location:166 → 378
      CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
      cl26098
      Location:32 → 145
      AAA_33; AAA domain

    3. XM_010816213.4 → XP_010814515.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X2

      See identical proteins and their annotated locations for XP_010814515.1

      UniProtKB/Swiss-Prot
      P06623, Q3SZJ6
      Conserved Domains (2) summary
      pfam05881
      Location:166 → 378
      CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
      cl26098
      Location:32 → 145
      AAA_33; AAA domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P06623.2 GenPept UniProtKB/Swiss-Prot:P06623

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials