U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Ir52b Ionotropic receptor 52b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246631, updated on 11-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Ir52bprovided by FlyBase
    Official Full Name
    Ionotropic receptor 52bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050469
    Locus tag
    Dmel_CG30469
    See related
    AllianceGenome:FB:FBgn0050469
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    52b; CG12961; CG30469; DmelIR52b; Dmel\CG30469; IF52b; IR52b
    Summary
    Predicted to enable ligand-gated ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be integral component of membrane. Is expressed in mesothoracic leg taste bristle chemosensory neurons; metathoracic leg taste bristle chemosensory neurons; prothoracic leg taste bristle chemosensory neurons; and wing. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Ir52b in Genome Data Viewer
    Location:
    52A6-52A6; 2-74 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15501820..15503610)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11389325..11391115)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 52a Neighboring gene Ionotropic receptor 52c Neighboring gene Ionotropic receptor 52d

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The Drosophila IR20a clade of ionotropic receptors are candidate taste and pheromone receptors. Koh TW, et al. Neuron, 2014 Aug 20. PMID 25123314, Free PMC Article
    2. A Molecular and Cellular Context-Dependent Role for Ir76b in Detection of Amino Acid Taste. Ganguly A, et al. Cell Rep, 2017 Jan 17. PMID 28099851, Free PMC Article
    3. An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing. Sánchez-Alcañiz JA, et al. Nat Commun, 2018 Oct 12. PMID 30315166, Free PMC Article
    4. The Structure and Function of Ionotropic Receptors in Drosophila. Ni L. Front Mol Neurosci, 2020. PMID 33597847, Free PMC Article
    5. Ancient protostome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction. Croset V, et al. PLoS Genet, 2010 Aug 19. PMID 20808886, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ionotropic receptor 52b
    Names
    CG30469-PB
    Ir52b-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      15501820..15503610
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166097.2 → NP_725469.2  ionotropic receptor 52b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725469.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZA15
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZA15 A1ZA15

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools