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    Tenm4 teneurin transmembrane protein 4 [ Mus musculus (house mouse) ]

    Gene ID: 23966, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Tenm4provided by MGI
    Official Full Name
    teneurin transmembrane protein 4provided by MGI
    Primary source
    MGI:MGI:2447063
    See related
    Ensembl:ENSMUSG00000048078 AllianceGenome:MGI:2447063
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Doc4; ELM2; Odz4; l7Rn3; Ten-m4; l(7)-3Rn; mKIAA1302
    Summary
    Enables protein homodimerization activity. Involved in several processes, including central nervous system myelin formation; positive regulation of gastrulation; and regulation of nervous system development. Acts upstream of or within cardiac cell fate specification; cardiac muscle cell proliferation; and gastrulation with mouth forming second. Located in several cellular components, including neuron projection; nucleus; and plasma membrane. Is active in glutamatergic synapse. Is expressed in several structures, including branchial arch; central nervous system; future brain; somite; and upper leg. Human ortholog(s) of this gene implicated in essential tremor 5. Orthologous to human TENM4 (teneurin transmembrane protein 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in ovary adult (RPKM 25.2), subcutaneous fat pad adult (RPKM 11.8) and 10 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tenm4 in Genome Data Viewer
    Location:
    7 E1; 7 52.53 cM
    Exon count:
    42
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (95550262..96560300)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (96171244..96911093)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 57510 Neighboring gene STARR-seq mESC enhancer starr_19553 Neighboring gene predicted gene, 39049 Neighboring gene STARR-seq mESC enhancer starr_19555 Neighboring gene frataxin pseudogene Neighboring gene STARR-seq mESC enhancer starr_19557 Neighboring gene STARR-seq mESC enhancer starr_19558 Neighboring gene STARR-seq mESC enhancer starr_19562 Neighboring gene STARR-seq mESC enhancer starr_19563 Neighboring gene STARR-seq mESC enhancer starr_19564 Neighboring gene STARR-seq mESC enhancer starr_19567 Neighboring gene predicted gene 8319 Neighboring gene STARR-seq mESC enhancer starr_19570 Neighboring gene microRNA 708 Neighboring gene microRNA 6394 Neighboring gene predicted gene 15412 Neighboring gene STARR-seq mESC enhancer starr_19572 Neighboring gene ribosomal protein S11, pseudogene 5 Neighboring gene VISTA enhancer mm2003 Neighboring gene STARR-seq mESC enhancer starr_19576 Neighboring gene STARR-seq mESC enhancer starr_19579 Neighboring gene STARR-seq mESC enhancer starr_19580 Neighboring gene predicted gene 15413 Neighboring gene STARR-seq mESC enhancer starr_19583 Neighboring gene STARR-positive B cell enhancer mm9_chr7:104099810-104100111 Neighboring gene STARR-positive B cell enhancer mm9_chr7:104119017-104119317 Neighboring gene STARR-seq mESC enhancer starr_19585 Neighboring gene predicted gene, 22226 Neighboring gene asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The extracellular domain of teneurin-4 promotes cell adhesion for oligodendrocyte differentiation. Hayashi C, et al. Biochem Biophys Res Commun, 2020 Feb 26. PMID 31839217
    2. Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling. Suzuki N, et al. FASEB J, 2014 Mar. PMID 24344332, Free PMC Article
    3. Muscle Satellite Cell Protein Teneurin-4 Regulates Differentiation During Muscle Regeneration. Ishii K, et al. Stem Cells, 2015 Oct. PMID 26013034, Free PMC Article
    4. Development of type I/II oligodendrocytes regulated by teneurin-4 in the murine spinal cord. Hayashi C, et al. Sci Rep, 2020 May 25. PMID 32451386, Free PMC Article
    5. Ten-m4 plays a unique role in the establishment of binocular visual circuits. Young TR, et al. Dev Neurobiol, 2023 Apr-May. PMID 37092850

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Ten-m4 plays a unique role in the establishment of binocular visual circuits.
      Title: Ten-m4 plays a unique role in the establishment of binocular visual circuits.
    2. The extracellular domain of teneurin-4 promotes cell adhesion for oligodendrocyte differentiation.
      Title: The extracellular domain of teneurin-4 promotes cell adhesion for oligodendrocyte differentiation.
    3. our findings revealed that Ten-4 functions as a crucial player in maintaining the quiescence of muscle satellite cells
      Title: Muscle Satellite Cell Protein Teneurin-4 Regulates Differentiation During Muscle Regeneration.
    4. Ten-4 suppresses chondrogenic differentiation and regulates the expression and activation of the key molecules for chondrogenesis
      Title: Teneurin-4, a transmembrane protein, is a novel regulator that suppresses chondrogenic differentiation.
    5. data demonstrate that Tenm4 mutants fail to form a primitive streak and to induce embryonic mesoderm
      Title: Mouse Tenm4 is required for mesoderm induction.
    6. The results of this study suggested that Ten-4 is a novel regulator of oligodendrocyte differentiation and that it plays a critical role in the myelination of small-diameter axons in the CNS.
      Title: Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS.
    Submit: New GeneRIF Correction

    Phenotypes

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    Associated conditions

    Description Tests
    lethal, Chr 7, Rinchik 3
    GeneReviews: Not available

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein heterodimerization activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein homodimerization activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cardiac cell fate specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cardiac muscle cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in central nervous system myelin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in central nervous system myelin formation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in central nervous system myelin formation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within gastrulation with mouth forming second IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuron development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuron development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in neuron development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of gastrulation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of myelination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of oligodendrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of myelination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of myelination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in synaptic membrane adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in synaptic membrane adhesion NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    teneurin-4
    Names
    downstream of CHOP4
    odd Oz/ten-m homolog 4
    protein Odd Oz/ten-m homolog 4
    ten-4
    tenascin-M4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310760.1 → NP_001297689.1  teneurin-4 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC073599, AC162370, AK147579, BE980985
      Consensus CDS
      CCDS80753.1
      UniProtKB/Swiss-Prot
      Q3UHK6
      Related
      ENSMUSP00000102783.2, ENSMUST00000107165.8
      Conserved Domains (8) summary
      COG3209
      Location:1666 → 2362
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1296 → 1335
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2446 → 2525
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1286 → 1627
      NHL; NHL repeat unit of beta-propeller proteins
      pfam01414
      Location:808 → 850
      DSL; Delta serrate ligand
      pfam01500
      Location:691 → 839
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam06484
      Location:36 → 402
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2749 → 2826
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

    2. NM_001310762.1 → NP_001297691.1  teneurin-4 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, uses a downstream start codon, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. It encodes isoform 3, which is shorter than isoform 1.
      Source sequence(s)
      AC073599, AC116683, AC158136, AC162370, AK147579, BE980985
      Consensus CDS
      CCDS80754.1
      UniProtKB/Swiss-Prot
      Q3UHK6
      Related
      ENSMUSP00000102780.2, ENSMUST00000107162.8
      Conserved Domains (10) summary
      COG3209
      Location:1738 → 2494
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1333 → 1382
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1732 → 1772
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2438 → 2517
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:699 → 847
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam06484
      Location:11 → 410
      Ten_N; Teneurin Intracellular Region
      pfam07974
      Location:703 → 729
      EGF_2; EGF-like domain
      pfam15636
      Location:2743 → 2818
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1285 → 1619
      NHL; NHL repeat unit of beta-propeller proteins
      cl19567
      Location:817 → 858
      DSL; Delta serrate ligand

    3. NM_011858.4 → NP_035988.2  teneurin-4 isoform 2

      See identical proteins and their annotated locations for NP_035988.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
      Source sequence(s)
      AC162370, AK147329, BE980985
      Consensus CDS
      CCDS40024.1
      UniProtKB/Swiss-Prot
      Q3UHK6
      Related
      ENSMUSP00000102784.2, ENSMUST00000107166.8
      Conserved Domains (8) summary
      COG3209
      Location:1629 → 2325
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1259 → 1298
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2409 → 2488
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1249 → 1590
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 365
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2712 → 2789
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:593 → 728
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:772 → 813
      DSL; Delta serrate ligand

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      95550262..96560300
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153061.1 → XP_036008954.1  teneurin-4 isoform X10

      Conserved Domains (8) summary
      COG3209
      Location:1699 → 2395
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1329 → 1368
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2479 → 2558
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1319 → 1660
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 435
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2782 → 2859
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:663 → 798
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:842 → 883
      DSL; Delta serrate ligand

    2. XM_006507806.4 → XP_006507869.1  teneurin-4 isoform X10

      See identical proteins and their annotated locations for XP_006507869.1

      Conserved Domains (8) summary
      COG3209
      Location:1699 → 2395
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1329 → 1368
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2479 → 2558
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1319 → 1660
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 435
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2782 → 2859
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:663 → 798
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:842 → 883
      DSL; Delta serrate ligand

    3. XM_030242548.1 → XP_030098408.1  teneurin-4 isoform X14

      Conserved Domains (8) summary
      COG3209
      Location:1629 → 2325
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1259 → 1298
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2409 → 2488
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1249 → 1590
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 365
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2712 → 2789
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:593 → 728
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:772 → 813
      DSL; Delta serrate ligand

    4. XM_036153067.1 → XP_036008960.1  teneurin-4 isoform X16

      Conserved Domains (8) summary
      COG3209
      Location:1596 → 2292
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1226 → 1265
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2376 → 2455
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1216 → 1557
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 332
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2679 → 2756
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:560 → 695
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:739 → 780
      DSL; Delta serrate ligand

    5. XM_036153070.1 → XP_036008963.1  teneurin-4 isoform X17

      Conserved Domains (7) summary
      COG3209
      Location:1587 → 2283
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1217 → 1256
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2367 → 2446
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1207 → 1548
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 332
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2670 → 2747
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:560 → 821
      exchanger_TraA; outer membrane exchange protein TraA

    6. XM_006507804.2 → XP_006507867.1  teneurin-4 isoform X10

      See identical proteins and their annotated locations for XP_006507867.1

      Conserved Domains (8) summary
      COG3209
      Location:1699 → 2395
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1329 → 1368
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2479 → 2558
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1319 → 1660
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 435
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2782 → 2859
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:663 → 798
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:842 → 883
      DSL; Delta serrate ligand

    7. XM_030242546.1 → XP_030098406.1  teneurin-4 isoform X13

      Conserved Domains (8) summary
      COG3209
      Location:1666 → 2362
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1296 → 1335
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2446 → 2525
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1286 → 1627
      NHL; NHL repeat unit of beta-propeller proteins
      pfam01414
      Location:808 → 850
      DSL; Delta serrate ligand
      pfam01500
      Location:691 → 839
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam06484
      Location:36 → 402
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2749 → 2826
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

    8. XM_030242544.1 → XP_030098404.1  teneurin-4 isoform X11

      Conserved Domains (8) summary
      COG3209
      Location:1674 → 2370
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1304 → 1343
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2454 → 2533
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1294 → 1635
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 410
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2757 → 2834
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:638 → 773
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:817 → 858
      DSL; Delta serrate ligand

    9. XM_030242550.1 → XP_030098410.1  teneurin-4 isoform X15

      UniProtKB/Swiss-Prot
      O70465, Q3TSI0, Q3UH52, Q3UHK6, Q80TF5, Q9WTS7
      Conserved Domains (8) summary
      COG3209
      Location:1604 → 2300
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1234 → 1273
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2384 → 2463
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1224 → 1565
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 340
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2687 → 2764
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:568 → 703
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:747 → 788
      DSL; Delta serrate ligand

    10. XM_030242545.1 → XP_030098405.1  teneurin-4 isoform X11

      Conserved Domains (8) summary
      COG3209
      Location:1674 → 2370
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1304 → 1343
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2454 → 2533
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1294 → 1635
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 410
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2757 → 2834
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:638 → 773
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:817 → 858
      DSL; Delta serrate ligand

    11. XM_030242551.1 → XP_030098411.1  teneurin-4 isoform X15

      UniProtKB/Swiss-Prot
      O70465, Q3TSI0, Q3UH52, Q3UHK6, Q80TF5, Q9WTS7
      Conserved Domains (8) summary
      COG3209
      Location:1604 → 2300
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1234 → 1273
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2384 → 2463
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1224 → 1565
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 340
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2687 → 2764
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:568 → 703
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:747 → 788
      DSL; Delta serrate ligand

    12. XM_036153062.1 → XP_036008955.1  teneurin-4 isoform X11

      Conserved Domains (8) summary
      COG3209
      Location:1674 → 2370
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1304 → 1343
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2454 → 2533
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1294 → 1635
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 410
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2757 → 2834
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:638 → 773
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:817 → 858
      DSL; Delta serrate ligand

    13. XM_036153066.1 → XP_036008959.1  teneurin-4 isoform X15

      UniProtKB/Swiss-Prot
      O70465, Q3TSI0, Q3UH52, Q3UHK6, Q80TF5, Q9WTS7
      Conserved Domains (8) summary
      COG3209
      Location:1604 → 2300
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1234 → 1273
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2384 → 2463
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1224 → 1565
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 340
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2687 → 2764
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:568 → 703
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:747 → 788
      DSL; Delta serrate ligand

    14. XM_036153052.1 → XP_036008945.1  teneurin-4 isoform X1

      Conserved Domains (8) summary
      COG3209
      Location:1817 → 2513
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1447 → 1486
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2597 → 2676
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1437 → 1778
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:154 → 553
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2900 → 2977
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:781 → 916
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:960 → 1001
      DSL; Delta serrate ligand

    15. XM_036153053.1 → XP_036008946.1  teneurin-4 isoform X2

      Conserved Domains (8) summary
      COG3209
      Location:1810 → 2506
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1447 → 1475
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2590 → 2669
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1437 → 1771
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:154 → 553
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2893 → 2970
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:781 → 916
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:960 → 1001
      DSL; Delta serrate ligand

    16. XM_036153054.1 → XP_036008947.1  teneurin-4 isoform X3

      Conserved Domains (7) summary
      COG3209
      Location:1808 → 2504
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1438 → 1477
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2588 → 2667
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1428 → 1769
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:154 → 553
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2891 → 2968
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:781 → 1042
      exchanger_TraA; outer membrane exchange protein TraA

    17. XM_036153055.1 → XP_036008948.1  teneurin-4 isoform X4

      Conserved Domains (7) summary
      COG3209
      Location:1801 → 2497
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1438 → 1466
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2581 → 2660
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1428 → 1762
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:154 → 553
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2884 → 2961
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:781 → 1042
      exchanger_TraA; outer membrane exchange protein TraA

    18. XM_036153056.1 → XP_036008949.1  teneurin-4 isoform X5

      Conserved Domains (8) summary
      COG3209
      Location:1784 → 2480
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1414 → 1453
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2564 → 2643
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1404 → 1745
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:154 → 520
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2867 → 2944
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:748 → 883
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:927 → 968
      DSL; Delta serrate ligand

    19. XM_036153072.1 → XP_036008965.1  teneurin-4 isoform X21

      Conserved Domains (8) summary
      COG3209
      Location:1777 → 2473
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1414 → 1442
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2557 → 2636
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1404 → 1738
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:154 → 520
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2860 → 2937
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:748 → 883
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:927 → 968
      DSL; Delta serrate ligand

    20. XM_036153057.1 → XP_036008950.1  teneurin-4 isoform X6

      Conserved Domains (7) summary
      COG3209
      Location:1775 → 2471
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1405 → 1444
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2555 → 2634
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1395 → 1736
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:154 → 520
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2858 → 2935
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:748 → 1009
      exchanger_TraA; outer membrane exchange protein TraA

    21. XM_036153058.1 → XP_036008951.1  teneurin-4 isoform X7

      Conserved Domains (8) summary
      COG3209
      Location:1747 → 2443
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1377 → 1416
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2527 → 2606
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1367 → 1708
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:154 → 483
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2830 → 2907
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:711 → 846
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:890 → 931
      DSL; Delta serrate ligand

    22. XM_036153059.1 → XP_036008952.1  teneurin-4 isoform X9

      Conserved Domains (8) summary
      COG3209
      Location:1714 → 2410
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1344 → 1383
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2494 → 2573
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1334 → 1675
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:154 → 450
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2797 → 2874
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:678 → 813
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:857 → 898
      DSL; Delta serrate ligand

    23. XM_030242552.1 → XP_030098412.1  teneurin-4 isoform X18

      Conserved Domains (8) summary
      COG3209
      Location:1571 → 2267
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1201 → 1240
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2351 → 2430
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1191 → 1532
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 307
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2654 → 2731
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:535 → 670
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:714 → 755
      DSL; Delta serrate ligand

    24. XM_006507805.3 → XP_006507868.1  teneurin-4 isoform X10

      See identical proteins and their annotated locations for XP_006507868.1

      Conserved Domains (8) summary
      COG3209
      Location:1699 → 2395
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1329 → 1368
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2479 → 2558
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1319 → 1660
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 435
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2782 → 2859
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:663 → 798
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:842 → 883
      DSL; Delta serrate ligand

    25. XM_030242549.2 → XP_030098409.1  teneurin-4 isoform X14

      Conserved Domains (8) summary
      COG3209
      Location:1629 → 2325
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1259 → 1298
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2409 → 2488
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1249 → 1590
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 365
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2712 → 2789
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:593 → 728
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:772 → 813
      DSL; Delta serrate ligand

    26. XM_036153060.1 → XP_036008953.1  teneurin-4 isoform X10

      Conserved Domains (8) summary
      COG3209
      Location:1699 → 2395
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1329 → 1368
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2479 → 2558
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1319 → 1660
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 435
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2782 → 2859
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:663 → 798
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:842 → 883
      DSL; Delta serrate ligand

    27. XM_036153069.1 → XP_036008962.1  teneurin-4 isoform X16

      Conserved Domains (8) summary
      COG3209
      Location:1596 → 2292
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1226 → 1265
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2376 → 2455
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1216 → 1557
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 332
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2679 → 2756
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:560 → 695
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:739 → 780
      DSL; Delta serrate ligand

    28. XM_006507807.5 → XP_006507870.1  teneurin-4 isoform X11

      See identical proteins and their annotated locations for XP_006507870.1

      Conserved Domains (8) summary
      COG3209
      Location:1674 → 2370
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1304 → 1343
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2454 → 2533
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1294 → 1635
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 410
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2757 → 2834
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:638 → 773
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:817 → 858
      DSL; Delta serrate ligand

    29. XM_036153065.1 → XP_036008958.1  teneurin-4 isoform X15

      UniProtKB/Swiss-Prot
      O70465, Q3TSI0, Q3UH52, Q3UHK6, Q80TF5, Q9WTS7
      Conserved Domains (8) summary
      COG3209
      Location:1604 → 2300
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1234 → 1273
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2384 → 2463
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1224 → 1565
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 340
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2687 → 2764
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:568 → 703
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:747 → 788
      DSL; Delta serrate ligand

    30. XM_036153071.1 → XP_036008964.1  teneurin-4 isoform X18

      Conserved Domains (8) summary
      COG3209
      Location:1571 → 2267
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1201 → 1240
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2351 → 2430
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1191 → 1532
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 307
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2654 → 2731
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:535 → 670
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:714 → 755
      DSL; Delta serrate ligand

    31. XM_006507803.5 → XP_006507866.1  teneurin-4 isoform X10

      See identical proteins and their annotated locations for XP_006507866.1

      Conserved Domains (8) summary
      COG3209
      Location:1699 → 2395
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1329 → 1368
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2479 → 2558
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1319 → 1660
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 435
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2782 → 2859
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:663 → 798
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:842 → 883
      DSL; Delta serrate ligand

    32. XM_036153064.1 → XP_036008957.1  teneurin-4 isoform X14

      Conserved Domains (8) summary
      COG3209
      Location:1629 → 2325
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1259 → 1298
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2409 → 2488
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1249 → 1590
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 365
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2712 → 2789
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:593 → 728
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:772 → 813
      DSL; Delta serrate ligand

    33. XM_036153068.1 → XP_036008961.1  teneurin-4 isoform X16

      Conserved Domains (8) summary
      COG3209
      Location:1596 → 2292
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1226 → 1265
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2376 → 2455
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1216 → 1557
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:36 → 332
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2679 → 2756
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:560 → 695
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:739 → 780
      DSL; Delta serrate ligand

    34. XM_006507808.5 → XP_006507871.1  teneurin-4 isoform X11

      See identical proteins and their annotated locations for XP_006507871.1

      Conserved Domains (8) summary
      COG3209
      Location:1674 → 2370
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1304 → 1343
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2454 → 2533
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1294 → 1635
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 410
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2757 → 2834
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:638 → 773
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:817 → 858
      DSL; Delta serrate ligand

    35. XM_006507801.5 → XP_006507864.1  teneurin-4 isoform X8

      Conserved Domains (8) summary
      COG3209
      Location:1740 → 2436
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1370 → 1409
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2520 → 2599
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1360 → 1701
      NHL; NHL repeat unit of beta-propeller proteins
      pfam01414
      Location:882 → 924
      DSL; Delta serrate ligand
      pfam01500
      Location:765 → 913
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam06484
      Location:77 → 476
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2823 → 2900
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

    36. XM_036153063.1 → XP_036008956.1  teneurin-4 isoform X12

      Conserved Domains (8) summary
      COG3209
      Location:1670 → 2366
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1300 → 1339
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2450 → 2529
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1290 → 1631
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:77 → 406
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2753 → 2830
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:634 → 769
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:813 → 854
      DSL; Delta serrate ligand

    37. XM_011241793.1 → XP_011240095.1  teneurin-4 isoform X11

      See identical proteins and their annotated locations for XP_011240095.1

      Conserved Domains (8) summary
      COG3209
      Location:1674 → 2370
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1304 → 1343
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2454 → 2533
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1294 → 1635
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:11 → 410
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2757 → 2834
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:638 → 773
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:817 → 858
      DSL; Delta serrate ligand

    38. XM_006507812.5 → XP_006507875.1  teneurin-4 isoform X19

      Conserved Domains (7) summary
      COG3209
      Location:852 → 1548
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:51 → 80
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:482 → 521
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:1632 → 1711
      Rhs_assc_core; RHS repeat-associated core domain
      pfam07974
      Location:10 → 36
      EGF_2; EGF-like domain
      cl18310
      Location:472 → 813
      NHL; NHL repeat unit of beta-propeller proteins
      pfam15636
      Location:1935 → 2012
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

    39. XM_006507813.5 → XP_006507876.1  teneurin-4 isoform X20

      Conserved Domains (7) summary
      COG3209
      Location:843 → 1539
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:42 → 71
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:473 → 512
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:1623 → 1702
      Rhs_assc_core; RHS repeat-associated core domain
      pfam07974
      Location:10 → 36
      EGF_2; EGF-like domain
      cl18310
      Location:463 → 804
      NHL; NHL repeat unit of beta-propeller proteins
      pfam15636
      Location:1926 → 2003
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UHK6.2 GenPept UniProtKB/Swiss-Prot:Q3UHK6

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