Mrps27 mitochondrial ribosomal protein S27 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mrps27provided by MGI
Official Full Name: mitochondrial ribosomal protein S27provided by MGI
Primary source: MGI:MGI:1919064
See related: Ensembl:ENSMUSG00000041632 AllianceGenome:MGI:1919064
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2610028H14Rik
Summary: Predicted to enable mitochondrial ribosome binding activity; rRNA binding activity; and tRNA binding activity. Predicted to be involved in cell population proliferation and positive regulation of mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; extraembryonic component; gonad; nervous system; and sensory organ. Orthologous to human MRPS27 (mitochondrial ribosomal protein S27). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in heart adult (RPKM 13.1), CNS E11.5 (RPKM 12.5) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 13 D1; 13 52.83 cM

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (99481275..99552070)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (99344767..99415562)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables mitochondrial ribosome binding	ISO Inferred from Sequence Orthology more info
enables mitochondrial ribosome binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables rRNA binding	ISO Inferred from Sequence Orthology more info
enables rRNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables tRNA binding	ISO Inferred from Sequence Orthology more info
enables tRNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in cell population proliferation	ISO Inferred from Sequence Orthology more info
involved_in cell population proliferation	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial translation	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of mitochondrial translation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of mitochondrial translation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	NAS Non-traceable Author Statement more info	PubMed
part_of mitochondrial small ribosomal subunit	ISO Inferred from Sequence Orthology more info
part_of mitochondrial small ribosomal subunit	ISS Inferred from Sequence or Structural Similarity more info
part_of mitochondrial small ribosomal subunit	NAS Non-traceable Author Statement more info	PubMed
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: small ribosomal subunit protein mS27

Names: 28S ribosomal protein S27, mitochondrial; MRP-S27; S27mt

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_173757.3 → NP_776118.2 small ribosomal subunit protein mS27

See identical proteins and their annotated locations for NP_776118.2

Status: VALIDATED

Source sequence(s)

AA461997, AK076008, AK087686

Consensus CDS

CCDS26722.1

UniProtKB/Swiss-Prot

E9QKZ5, Q8BK72

Related

ENSMUSP00000062326.6, ENSMUST00000052249.7

Conserved Domains (2) summary

sd00004
Location:111 → 135

PPR; PPR repeat [structural motif]

pfam10037
Location:1 → 412

MRP-S27; Mitochondrial 28S ribosomal protein S27

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000079.7 Reference GRCm39 C57BL/6J

Range

99481275..99552070

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006517602.1 → XP_006517665.1 small ribosomal subunit protein mS27 isoform X1

Conserved Domains (2) summary

sd00004
Location:182 → 212

PPR; PPR repeat [structural motif]

pfam10037
Location:1 → 453

MRP-S27; Mitochondrial 28S ribosomal protein S27
XM_017315495.2 → XP_017170984.1 small ribosomal subunit protein mS27 isoform X2

Conserved Domains (2) summary

sd00004
Location:112 → 142

PPR; PPR repeat [structural motif]

pfam10037
Location:25 → 383

MRP-S27; Mitochondrial 28S ribosomal protein S27
XM_017315496.2 → XP_017170985.1 small ribosomal subunit protein mS27 isoform X3

Conserved Domains (2) summary

sd00004
Location:41 → 65

PPR; PPR repeat [structural motif]

pfam10037
Location:25 → 342

MRP-S27; Mitochondrial 28S ribosomal protein S27
XM_036158019.1 → XP_036013912.1 small ribosomal subunit protein mS27 isoform X4

UniProtKB/TrEMBL

Q80ZI4

Conserved Domains (2) summary

sd00004
Location:33 → 63

PPR; PPR repeat [structural motif]

pfam10037
Location:25 → 304

MRP-S27; Mitochondrial 28S ribosomal protein S27