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    sra-1 Serpentine receptor class alpha-1 [ Caenorhabditis elegans ]

    Gene ID: 191772, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sra-1
    Official Full Name
    Serpentine receptor class alpha-1
    Primary source
    WormBase:WBGene00005027
    Locus tag
    CELE_AH6.4
    See related
    AllianceGenome:WB:WBGene00005027
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in male. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See sra-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (9520200..9521670, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Receptor-type guanylate cyclase gcy-1 Neighboring gene Sideroflexin-1.1 Neighboring gene Uncharacterized protein Neighboring gene PP_kinase_C domain-containing protein Neighboring gene Zinc finger protein mex-6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Family-B G-protein-coupled receptors. Harmar AJ. Genome Biol, 2001. PMID 11790261, Free PMC Article
    2. Genome-wide analysis of sex-enriched gene expression during C. elegans larval development. Thoemke K, et al. Dev Biol, 2005 Aug 15. PMID 15987632
    3. Genome-wide analysis of developmental and sex-regulated gene expression profiles in Caenorhabditis elegans. Jiang M, et al. Proc Natl Acad Sci U S A, 2001 Jan 2. PMID 11134517, Free PMC Article
    4. The C. elegans G-protein-coupled receptor SRA-13 inhibits RAS/MAPK signalling during olfaction and vulval development. Battu G, et al. Development, 2003 Jun. PMID 12736202
    5. Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. Troemel ER, et al. Cell, 1995 Oct 20. PMID 7585938

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of chemical stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Serpentine receptor class alpha-1
    NP_496042.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9520200..9521670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063641.4 → NP_496042.1  Serpentine receptor class alpha-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496042.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09203
      Conserved Domains (1) summary
      pfam02117
      Location:1 → 328
      7TM_GPCR_Sra; Serpentine type 7TM GPCR chemoreceptor Sra
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09203.1

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