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    snf-10 Transporter [ Caenorhabditis elegans ]

    Gene ID: 191769, updated on 18-Sep-2024

    Summary

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    Official Symbol
    snf-10
    Official Full Name
    Transporter
    Primary source
    WormBase:WBGene00004909
    Locus tag
    CELE_Y32F6A.2
    See related
    AllianceGenome:WB:WBGene00004909
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Involved in positive regulation of amoeboid sperm motility. Located in cell body membrane. Is expressed in germ line; sperm; spermatid; and spermatocyte. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See snf-10 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (10438330..10440823, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Amino acid transporter transmembrane domain-containing protein Neighboring gene ncRNA Neighboring gene SET domain-containing protein Neighboring gene Poly(A) polymerase Neighboring gene Retinoid-inducible serine carboxypeptidase Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SLC6 family transporter SNF-10 is required for protease-mediated activation of sperm motility in C. elegans. Fenker KE, et al. Dev Biol, 2014 Sep 1. PMID 24929237, Free PMC Article
    2. SNF-10 connects male-derived signals to the onset of sperm motility in C. elegans. Fenker KE, et al. Worm, 2015 Jan-Mar. PMID 26430556, Free PMC Article
    3. An RNAi screen identifies genes that regulate GABA synapses. Vashlishan AB, et al. Neuron, 2008 May 8. PMID 18466746
    4. A database of Caenorhabditis elegans behavioral phenotypes. Yemini E, et al. Nat Methods, 2013 Sep. PMID 23852451, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables amino acid:sodium symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-alpha-amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in gamma-aminobutyric acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycine import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of amoeboid sperm motility IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cell body membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Transporter
    NP_505682.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10438330..10440823 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073281.4 → NP_505682.2  Transporter [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505682.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45915
      Conserved Domains (1) summary
      cl11976
      Location:78 → 628
      SNF; Sodium:neurotransmitter symporter family
    Nucleotide Protein
    Heading Accession and Version

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