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    nol-9 Polynucleotide 5'-hydroxyl-kinase nol-9 [ Caenorhabditis elegans ]

    Gene ID: 187190, updated on 18-Sep-2024

    Summary

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    Official Symbol
    nol-9
    Official Full Name
    Polynucleotide 5'-hydroxyl-kinase nol-9
    Primary source
    WormBase:WBGene00010709
    Locus tag
    CELE_K09B11.2
    See related
    AllianceGenome:WB:WBGene00010709
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable polynucleotide 5'-hydroxyl-kinase activity. Predicted to be involved in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be active in nucleus. Orthologous to human NOL9 (nucleolar protein 9). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See nol-9 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    10
    Sequence:
    Chromosome: IV; NC_003282.8 (13422500..13429399)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Transcription factor aptf-2 Neighboring gene Pelle-like serine/threonine-protein kinase pik-1 Neighboring gene ncRNA Neighboring gene Ovule protein Neighboring gene Tyrosine-protein kinase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Pothof J, et al. Genes Dev, 2003 Feb 15. PMID 12600937, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polynucleotide 5'-hydroxyl-kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polynucleotide 5'-hydroxyl-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polynucleotide 5'-hydroxyl-kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Polynucleotide 5'-hydroxyl-kinase nol-9
    NP_001255744.1
    • Confirmed by transcript evidence
    NP_001255745.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13422500..13429399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268815.2 → NP_001255744.1  Polynucleotide 5'-hydroxyl-kinase nol-9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255744.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3YT82, Q9U3B6
      Conserved Domains (1) summary
      pfam16575
      Location:190 → 376
      CLP1_P; mRNA cleavage and polyadenylation factor CLP1 P-loop

    2. NM_001268816.3 → NP_001255745.1  Polynucleotide 5'-hydroxyl-kinase nol-9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255745.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9U3B6
      Conserved Domains (1) summary
      pfam06807
      Location:16 → 80
      Clp1; Pre-mRNA cleavage complex II protein Clp1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9U3B6.1

    Gene LinkOut

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