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    gfi-3 Protein gfi-3 [ Caenorhabditis elegans ]

    Gene ID: 181544, updated on 18-Sep-2024

    Summary

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    Official Symbol
    gfi-3
    Official Full Name
    Protein gfi-3
    Primary source
    WormBase:WBGene00001583
    Locus tag
    CELE_M163.4
    See related
    AllianceGenome:WB:WBGene00001583
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein K11-linked ubiquitination. Predicted to be part of anaphase-promoting complex. Is expressed in germ line; intestine; and sperm. Orthologous to human ANAPC5 (anaphase promoting complex subunit 5). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See gfi-3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    16
    Sequence:
    Chromosome: X; NC_003284.9 (14480572..14484702)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene tRNA-Lys Neighboring gene ShKT domain-containing protein Neighboring gene ShKT domain-containing protein Neighboring gene ncRNA Neighboring gene tRNA-Lys

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple subunits of the Caenorhabditis elegans anaphase-promoting complex are required for chromosome segregation during meiosis I. Davis ES, et al. Genetics, 2002 Feb. PMID 11861581, Free PMC Article
    2. Functional redundancy of paralogs of an anaphase promoting complex/cyclosome subunit in Caenorhabditis elegans meiosis. Stein KK, et al. Genetics, 2010 Dec. PMID 20944012, Free PMC Article
    3. A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Green RA, et al. Cell, 2011 Apr 29. PMID 21529718, Free PMC Article
    4. Anaphase-promoting complex in Caenorhabditis elegans. Yeong FM. Mol Cell Biol, 2004 Mar. PMID 14993261, Free PMC Article
    5. Identification of cross-linked peptides from complex samples. Yang B, et al. Nat Methods, 2012 Sep. PMID 22772728

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of mitotic metaphase/anaphase transition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein K11-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of anaphase-promoting complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein gfi-3
    NP_510409.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      14480572..14484702
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078008.7 → NP_510409.1  Protein gfi-3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510409.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93903
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93903.1

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