exoc-7 Exocyst complex component 7 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: exoc-7
Official Full Name: Exocyst complex component 7
Primary source: WormBase:WBGene00016606
Locus tag: CELE_C43E11.8
See related: AllianceGenome:WB:WBGene00016606
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in exocytosis. Predicted to be located in cis-Golgi network and membrane. Predicted to be part of exocyst. Is expressed in several structures, including coelomocyte; intestine; somatic nervous system; tail neurons; and vulva. Orthologous to human EXOC7 (exocyst complex component 7). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See exoc-7 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 7

Sequence:: Chromosome: I; NC_003279.8 (4242821..4247582, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The findings identify novel, potential regulators for exocyst function and show that exoc-7 and exoc-8 are functionally linked to rab-10 in endosomal trafficking in intestinal epithelial cells in C. elegans.
Title: Exocyst subunits Exo70 and Exo84 cooperate with small GTPases to regulate behavior and endocytic trafficking in C. elegans.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C43E11.4 (e-PCR)
- UniSTS:308760

C43E11.8 (e-PCR)
- UniSTS:308762

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables phosphatidylinositol-4,5-bisphosphate binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol-4,5-bisphosphate binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in exocytosis	IEA Inferred from Electronic Annotation more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle tethering involved in exocytosis	IC Inferred by Curator more info

Component	Evidence Code	Pubs
part_of exocyst	IBA Inferred from Biological aspect of Ancestor more info
part_of exocyst	IEA Inferred from Electronic Annotation more info
part_of exocyst	ISS Inferred from Sequence or Structural Similarity more info	PubMed

General protein information

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Preferred Names: Exocyst complex component 7

NP_491337.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

4242821..4247582 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_058936.5 → NP_491337.1 Exocyst complex component 7 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_491337.1

Status: REVIEWED

UniProtKB/TrEMBL

P91149

Conserved Domains (1) summary

pfam03081
Location:371 → 620

Exo70; Exo70 exocyst complex subunit