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    inx-15 Innexin [ Caenorhabditis elegans ]

    Gene ID: 172004, updated on 18-Sep-2024

    Summary

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    Official Symbol
    inx-15
    Official Full Name
    Innexin
    Primary source
    WormBase:WBGene00002137
    Locus tag
    CELE_R12E2.9
    See related
    AllianceGenome:WB:WBGene00002137
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable gap junction channel activity. Predicted to be involved in ion transport and transmembrane transport. Predicted to be located in cell junction and membrane. Predicted to be integral component of membrane. Predicted to be active in gap junction and plasma membrane. Is expressed in intestine. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See inx-15 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (4159014..4161113, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Galaxin-like Neighboring gene Innexin-16 Neighboring gene Innexin-17

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans avermectin resistance and anesthetic response gene unc-9 encodes a member of a protein family implicated in electrical coupling of excitable cells. Barnes TM, et al. J Neurochem, 1997 Dec. PMID 9375655
    2. The role of gap junctions in Caenorhabditis elegans oocyte maturation and fertilization. Whitten SJ, et al. Dev Biol, 2007 Jan 15. PMID 16982048
    3. Systematic analysis of genes required for synapse structure and function. Sieburth D, et al. Nature, 2005 Jul 28. PMID 16049479
    4. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. Meissner B, et al. PLoS Genet, 2009 Jun. PMID 19557190, Free PMC Article
    5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables gap junction channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in gap junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in gap junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Innexin
    NP_491313.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4159014..4161113 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058912.6 → NP_491313.1  Innexin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491313.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61786
      Conserved Domains (1) summary
      pfam00876
      Location:18 → 377
      Innexin; Innexin
    Nucleotide Protein
    Heading Accession and Version

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