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    Hspbap1 HSPB1 associated protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171460, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Hspbap1provided by RGD
    Official Full Name
    HSPB1 associated protein 1provided by RGD
    Primary source
    RGD:620870
    See related
    EnsemblRapid:ENSRNOG00000002241 AllianceGenome:RGD:620870
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pass1
    Summary
    Predicted to enable 2-oxoglutarate-dependent dioxygenase activity. Predicted to be located in cytoplasm. Orthologous to human HSPBAP1 (HSPB1 associated protein 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 98.5), Kidney (RPKM 93.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Hspbap1 in Genome Data Viewer
    Location:
    11q22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (78445376..78500034, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (64940089..64994753, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (68142684..68197783, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene caspase 6, pseudogene 1 Neighboring gene poly (ADP-ribose) polymerase family, member 14 Neighboring gene small Cajal body-specific RNA 8 Neighboring gene solute carrier family 49 member 4 Neighboring gene uncharacterized LOC108352343 Neighboring gene metastasis associated 1 family, member 2, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of a novel protein from Sertoli cells, PASS1, that associates with mammalian small stress protein hsp27. Liu C, et al. J Biol Chem, 2000 Jun 23. PMID 10751411
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables 2-oxoglutarate-dependent dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    HSPB1-associated protein 1
    Names
    27 KdA heat shock protein-associated protein 1
    Hspb associated protein 1
    protein associated with small stress protein 1
    protein associating with small stress protein PASS1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134419.2 → NP_599246.2  HSPB1-associated protein 1

      See identical proteins and their annotated locations for NP_599246.2

      Status: VALIDATED

      Source sequence(s)
      BC091125
      UniProtKB/Swiss-Prot
      Q5BKC6, Q9R153
      UniProtKB/TrEMBL
      A6IRF3
      Related
      ENSRNOP00000003060.6, ENSRNOT00000003060.8
      Conserved Domains (1) summary
      pfam13621
      Location:37 → 272
      Cupin_8; Cupin-like domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      78445376..78500034 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039087950.2 → XP_038943878.1  HSPB1-associated protein 1 isoform X2

      UniProtKB/TrEMBL
      A6IRF4
      Conserved Domains (1) summary
      pfam13621
      Location:2 → 126
      Cupin_8; Cupin-like domain

    2. XM_039087949.2 → XP_038943877.1  HSPB1-associated protein 1 isoform X1

      Conserved Domains (1) summary
      pfam13621
      Location:3 → 135
      Cupin_8; Cupin-like domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BKC6.1 GenPept UniProtKB/Swiss-Prot:Q5BKC6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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