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    FBXW8 F-box and WD repeat domain containing 8 [ Canis lupus familiaris (dog) ]

    Gene ID: 106557503, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FBXW8provided by VGNC
    Official Full Name
    F-box and WD repeat domain containing 8provided by VGNC
    Primary source
    VGNC:VGNC:40798
    See related
    Ensembl:ENSCAFG00845026220
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See FBXW8 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (13780524..13901191)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (13515165..13635427)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (13854501..13975455)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (13742170..13863012)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (13820084..13940246)

    Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene ring finger protein, transmembrane 2 Neighboring gene uncharacterized LOC111092578 Neighboring gene harakiri, BCL2 interacting protein Neighboring gene uncharacterized LOC119866166 Neighboring gene uncharacterized LOC119866164 Neighboring gene uncharacterized LOC119866165 Neighboring gene tescalcin Neighboring gene U6 spliceosomal RNA Neighboring gene F-box protein 21

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cilium assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul7-RING ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in ciliary basal body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F-box/WD repeat-containing protein 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051830.1 Reference ROS_Cfam_1.0

      Range
      13780524..13901191
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038436826.1 → XP_038292754.1  F-box/WD repeat-containing protein 8

      UniProtKB/TrEMBL
      A0A8C0L0M9, A0A8C0L1R3, A0A8C0Z6R2, A0A8I3PSL2
      Related
      ENSCAFP00845036389.1, ENSCAFT00845046338.1
      Conserved Domains (4) summary
      COG2319
      Location:251 → 552
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:201 → 240
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:106 → 148
      F-box-like
      cl29593
      Location:183 → 307
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049286.1 Alternate UMICH_Zoey_3.1

      Range
      13742170..13863012
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038511729.1 → XP_038367657.1  F-box/WD repeat-containing protein 8

      Conserved Domains (4) summary
      COG2319
      Location:251 → 552
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:201 → 240
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:106 → 148
      F-box-like
      cl29593
      Location:183 → 307
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

      Range
      13820084..13940246
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038639410.1 → XP_038495338.1  F-box/WD repeat-containing protein 8

      Conserved Domains (4) summary
      COG2319
      Location:251 → 552
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:201 → 240
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:106 → 148
      F-box-like
      cl29593
      Location:183 → 307
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

      Range
      13854501..13975455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038575223.1 → XP_038431151.1  F-box/WD repeat-containing protein 8

      UniProtKB/TrEMBL
      A0A8C0L0M9

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      13515165..13635427
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038459190.1 → XP_038315118.1  F-box/WD repeat-containing protein 8

      UniProtKB/TrEMBL
      A0A8C0L0M9, A0A8C0L1R3, A0A8C0Z6R2, A0A8I3PSL2
      Conserved Domains (4) summary
      COG2319
      Location:251 → 552
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:201 → 240
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:106 → 148
      F-box-like
      cl29593
      Location:183 → 307
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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