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    PRODH2 proline dehydrogenase 2 [ Sus scrofa (pig) ]

    Gene ID: 106510519, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRODH2provided by VGNC
    Official Full Name
    proline dehydrogenase 2provided by VGNC
    Primary source
    VGNC:VGNC:91829
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Biased expression in kidney (RPKM 49.8), liver (RPKM 28.9) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See PRODH2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (45213712..45240437, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (40673972..40688103, complement)

    Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene proline and serine rich 3 Neighboring gene Rho GTPase activating protein 33 Neighboring gene NPHS1 adhesion molecule, nephrin Neighboring gene kirre like nephrin family adhesion molecule 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables proline dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proline catabolic process to glutamate IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable proline dehydrogenase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

      Range
      45213712..45240437 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021097118.1 → XP_020952777.1  probable proline dehydrogenase 2 isoform X10

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    2. XM_021097115.1 → XP_020952774.1  probable proline dehydrogenase 2 isoform X7

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    3. XM_021097114.1 → XP_020952773.1  probable proline dehydrogenase 2 isoform X6

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    4. XM_021097112.1 → XP_020952771.1  probable proline dehydrogenase 2 isoform X4

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    5. XM_021097111.1 → XP_020952770.1  probable proline dehydrogenase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1, A0A8D1ZSP5
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    6. XM_021097110.1 → XP_020952769.1  probable proline dehydrogenase 2 isoform X2

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    7. XM_021097120.1 → XP_020952779.1  probable proline dehydrogenase 2 isoform X12

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    8. XM_021097117.1 → XP_020952776.1  probable proline dehydrogenase 2 isoform X9

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    9. XM_021097116.1 → XP_020952775.1  probable proline dehydrogenase 2 isoform X8

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    10. XM_021097119.1 → XP_020952778.1  probable proline dehydrogenase 2 isoform X11

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    11. XM_021097109.1 → XP_020952768.1  probable proline dehydrogenase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (4) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase

    12. XM_021097113.1 → XP_020952772.1  probable proline dehydrogenase 2 isoform X5

      UniProtKB/TrEMBL
      A0A8D0NMC4, A0A8D1WDQ1
      Conserved Domains (5) summary
      cd00204
      Location:390 → 498
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:410 → 440
      ANK; ANK repeat [structural motif]
      cl21453
      Location:780 → 866
      PKc_like; Protein Kinases, catalytic domain
      cl26386
      Location:823 → 962
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl27530
      Location:10 → 399
      Pro_dh; Proline dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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