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    CCND2-AS1 CCND2 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 103752584, updated on 17-Sep-2024

    Summary

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    Official Symbol
    CCND2-AS1provided by HGNC
    Official Full Name
    CCND2 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:49398
    See related
    Ensembl:ENSG00000255920 AllianceGenome:HGNC:49398
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CCND2-AS2
    Expression
    Ubiquitous expression in adrenal (RPKM 4.8), brain (RPKM 4.4) and 25 other tissues See more
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    Genomic context

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    See CCND2-AS1 in Genome Data Viewer
    Location:
    12p13.32
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (4248767..4276184, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (4255526..4282943, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (4357933..4385350, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124900317 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:4226148-4227142 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5819 Neighboring gene ribosomal protein L18 pseudogene 9 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:4243897-4244502 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5820 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4256026-4256526 Neighboring gene CRISPRi-validated cis-regulatory element chr12.200 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4146 Neighboring gene uncharacterized LOC105369612 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5822 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4311299-4312200 Neighboring gene Sharpr-MPRA regulatory region 8601 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:4314426-4315336 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5823 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4147 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4148 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4149 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:4381043-4381234 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4150 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4151 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4152 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:4387997-4388189 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4389371-4390328 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5824 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4402781-4403282 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4403283-4403782 Neighboring gene cyclin D2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:4429971-4430624 Neighboring gene ribosomal protein S15 pseudogene 7 Neighboring gene TP53 induced glycolysis regulatory phosphatase Neighboring gene fibroblast growth factor 23

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LncRNA CCND2-AS1 promotes proliferation, migration, and invasion in papillary thyroid carcinoma. Xia E, et al. Biochem Biophys Res Commun, 2018 Feb 5. PMID 29366479
    2. Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling. Zhang H, et al. Biochem Biophys Res Commun, 2017 Jan 22. PMID 27923660
    3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Other Names

    • CCND2 antisense RNA 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_125790.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC006122
      Related
      ENST00000539135.1

    2. NR_149145.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC006122
      Related
      ENST00000646245.2

    3. NR_149146.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC006122

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      4248767..4276184 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      4255526..4282943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials