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    PDLIM2 PDZ and LIM domain 2 [ Macaca fascicularis (crab-eating macaque) ]

    Gene ID: 102126589, updated on 10-Oct-2024

    Summary

    Gene symbol
    PDLIM2
    Gene description
    PDZ and LIM domain 2
    See related
    Ensembl:ENSMFAG00000032463
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca fascicularis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See PDLIM2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 8 NC_088382.1 (25670759..25686921)
    102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 8 NC_052262.1 (21299287..21315442)

    Chromosome 8 - NC_088382.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 3 catalytic subunit gamma Neighboring gene transcription factor BTF3-like Neighboring gene sorbin and SH3 domain containing 3 Neighboring gene chromosome 8 C8orf58 homolog Neighboring gene cell cycle and apoptosis regulator 2 Neighboring gene bridging integrator 3

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables muscle alpha-actinin binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in heart development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in muscle structure development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    part_of filamentous actin IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in stress fiber IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    PDZ and LIM domain protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MFA8v1.0

    Genomic

    1. NC_088382.1 Reference T2T-MFA8v1.0

      Range
      25670759..25686921
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005562809.4XP_005562866.3  PDZ and LIM domain protein 2 isoform X1

    2. XM_015454572.3XP_015310058.3  PDZ and LIM domain protein 2 isoform X2

    3. XM_065518983.1XP_065375055.1  PDZ and LIM domain protein 2 isoform X4

    4. XM_015454573.3XP_015310059.3  PDZ and LIM domain protein 2 isoform X3

    5. XM_045398028.2XP_045253963.1  PDZ and LIM domain protein 2 isoform X5

      Conserved Domains (3) summary
      cd09449
      Location:286338
      LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
      cd00992
      Location:980
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:202255
      DUF4749; Domain of unknown function (DUF4749)
    6. XM_015454574.3XP_015310060.1  PDZ and LIM domain protein 2 isoform X5

      UniProtKB/Swiss-Prot
      Q9GKU1
      UniProtKB/TrEMBL
      A0A2K5V2E5
      Related
      ENSMFAP00000018913.1
      Conserved Domains (3) summary
      cd09449
      Location:286338
      LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
      cd00992
      Location:980
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:202255
      DUF4749; Domain of unknown function (DUF4749)
    7. XM_065518984.1XP_065375056.1  PDZ and LIM domain protein 2 isoform X5