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    MAPK1 mitogen-activated protein kinase 1 [ Ovis aries (sheep) ]

    Gene ID: 101115485, updated on 8-Mar-2024

    Summary

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    Gene symbol
    MAPK1
    Gene description
    mitogen-activated protein kinase 1
    See related
    EnsemblRapid:ENSOARG00020025998
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 17
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 17 NC_056070.1 (72035793..72094914)

    Chromosome 17 - NC_056070.1Genomic Context describing neighboring genes Neighboring gene DNA topoisomerase III beta Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1F Neighboring gene U6 spliceosomal RNA Neighboring gene yippee like 1 Neighboring gene peptidylprolyl isomerase like 2 Neighboring gene uncharacterized LOC114118901

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056070.1 Chromosome 17 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel epidermal growth factor-dependent extracellular signal-regulated MAP kinase cascade involved in sperm functionality in sheep. Luna C, et al. Biol Reprod, 2012 Oct. PMID 22786825

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A novel epidermal growth factor-dependent extracellular signal-regulated MAP kinase cascade involved in sperm functionality in sheep.
      Title: A novel epidermal growth factor-dependent extracellular signal-regulated MAP kinase cascade involved in sperm functionality in sheep.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056070.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      72035793..72094914
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042234178.1 → XP_042090112.1  mitogen-activated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      W5Q1R8
      Conserved Domains (1) summary
      cd07849
      Location:51 → 363
      STKc_ERK1_2_like; Catalytic domain of Extracellular signal-Regulated Kinase 1 and 2-like Serine/Threonine Kinases

    2. XM_027956867.2 → XP_027812668.2  mitogen-activated protein kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A836A080, W5Q1R8
      Related
      ENSOARP00020033914.2, ENSOART00020040889.2
      Conserved Domains (1) summary
      cd07849
      Location:19 → 353
      STKc_ERK1_2_like; Catalytic domain of Extracellular signal-Regulated Kinase 1 and 2-like Serine/Threonine Kinases
    Nucleotide Protein Strain
    Heading Accession and Version

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