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    HEY1 hes related family bHLH transcription factor with YRPW motif 1 [ Ovis aries (sheep) ]

    Gene ID: 101111557, updated on 8-Mar-2024

    Summary

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    Gene symbol
    HEY1
    Gene description
    hes related family bHLH transcription factor with YRPW motif 1
    See related
    EnsemblRapid:ENSOARG00020031903
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See HEY1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 9 NC_056062.1 (56050159..56053966, complement)

    Chromosome 9 - NC_056062.1Genomic Context describing neighboring genes Neighboring gene stathmin 2 Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene uncharacterized LOC132657180 Neighboring gene uncharacterized LOC132657181 Neighboring gene peptidyl-prolyl cis-trans isomerase A-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056062.1 Chromosome 9 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anterior/posterior pattern specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in circulatory system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neurogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hairy/enhancer-of-split related with YRPW motif protein 1
    Names
    hairy/enhancer-of-split related with YRPW motif 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056062.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      56050159..56053966 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004011756.6 → XP_004011805.2  hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A6P3ECB1, W5PDY7
      Related
      ENSOARP00020060780.1, ENSOART00020044214.1
      Conserved Domains (2) summary
      smart00511
      Location:120 → 166
      ORANGE; Orange domain
      cl00081
      Location:41 → 122
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    2. XM_042254355.2 → XP_042110289.1  hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1

      UniProtKB/TrEMBL
      W5PDY7
      Conserved Domains (2) summary
      smart00511
      Location:124 → 170
      ORANGE; Orange domain
      cl00081
      Location:41 → 126
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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