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    DLX3 distal-less homeobox 3 [ Ovis aries (sheep) ]

    Gene ID: 101109372, updated on 8-Mar-2024

    Summary

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    Gene symbol
    DLX3
    Gene description
    distal-less homeobox 3
    See related
    EnsemblRapid:ENSOARG00020011314
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See DLX3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 11 NC_056064.1 (36392045..36397231)

    Chromosome 11 - NC_056064.1Genomic Context describing neighboring genes Neighboring gene pyruvate dehydrogenase kinase 2 Neighboring gene integrin subunit alpha 3 Neighboring gene distal-less homeobox 4 Neighboring gene uncharacterized LOC106991422

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056064.1 Chromosome 11 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Characterization of a Single Nucleotide Polymorphism in the 3' Untranslated Region of Sheep DLX3 Gene. Rong E, et al. PLoS One, 2015. PMID 26332462, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in embryo development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in epithelial cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeobox protein DLX-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056064.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      36392045..36397231
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004012779.5 → XP_004012828.2  homeobox protein DLX-3

      UniProtKB/TrEMBL
      A0A6P3EHA8, C0L2S3, W5P6B8
      Related
      ENSOARP00020014228.1, ENSOART00020017234.2
      Conserved Domains (3) summary
      COG5576
      Location:109 → 232
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:132 → 186
      Homeobox; Homeobox domain
      pfam12413
      Location:27 → 107
      DLL_N; Homeobox protein distal-less-like N terminal
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials