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    GRM8 glutamate metabotropic receptor 8 [ Ovis aries (sheep) ]

    Gene ID: 101108742, updated on 8-Mar-2024

    Summary

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    Gene symbol
    GRM8
    Gene description
    glutamate metabotropic receptor 8
    See related
    EnsemblRapid:ENSOARG00020004541
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Also known as
    mGluR8
    Orthologs
    human mouse all
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    Genomic context

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    See GRM8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 4 NC_056057.1 (92332526..93226109, complement)

    Chromosome 4 - NC_056057.1Genomic Context describing neighboring genes Neighboring gene small ribosomal subunit protein eS1-like Neighboring gene large ribosomal subunit protein uL14-like Neighboring gene ATP synthase F(0) complex subunit C2, mitochondrial-like Neighboring gene craniofacial development protein 2-like Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene zinc finger protein 800

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056057.1 Chromosome 4 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables group III metabotropic glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled glutamate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metabotropic glutamate receptor 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056057.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      92332526..93226109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042248768.2 → XP_042104702.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A836A7X6
      Related
      ENSOARP00020005762.2, ENSOART00020006969.2
      Conserved Domains (3) summary
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:40 → 504
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:512 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_042248770.2 → XP_042104704.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A836A7X6
      Conserved Domains (3) summary
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:40 → 504
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:512 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    3. XM_042248771.2 → XP_042104705.1  metabotropic glutamate receptor 8 isoform X1

      UniProtKB/TrEMBL
      A0A836A7X6
      Conserved Domains (3) summary
      cd15454
      Location:582 → 892
      7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:40 → 504
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:512 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    4. XM_060415096.1 → XP_060271079.1  metabotropic glutamate receptor 8 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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