Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Naa80provided by RGD
Official Full Name: N(alpha)-acetyltransferase 80, NatH catalytic subunitprovided by RGD
Primary source: RGD:6496422
See related: EnsemblRapid:ENSRNOG00000054063 AllianceGenome:RGD:6496422
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Nat6
Summary: Predicted to enable acetyl-CoA binding activity and peptide alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal protein amino acid acetylation; actin modification; and regulation of actin polymerization or depolymerization. Predicted to be located in cytosol. Orthologous to human NAA80 (N-alpha-acetyltransferase 80, NatH catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Adrenal (RPKM 575.7), Lung (RPKM 199.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q32

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (117132957..117136207)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (108254314..108257564)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (116336441..116339691)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH139126 (e-PCR)
- UniSTS:221212

BF387601 (e-PCR)
- UniSTS:244420

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables N-acetyltransferase activity	ISO Inferred from Sequence Orthology more info
enables acetyl-CoA binding	ISO Inferred from Sequence Orthology more info
enables peptide alpha-N-acetyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in regulation of actin polymerization or depolymerization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: N-alpha-acetyltransferase 80

Names: N-acetyltransferase 6 (GCN5-related); N-acetyltransferase 6-like

NP_001291705.1

EC 2.3.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.