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    CNTFR ciliary neurotrophic factor receptor [ Ovis aries (sheep) ]

    Gene ID: 100885760, updated on 8-Mar-2024

    Summary

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    Gene symbol
    CNTFR
    Gene description
    ciliary neurotrophic factor receptor
    See related
    EnsemblRapid:ENSOARG00020006639
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See CNTFR in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (36976075..37039723)

    Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132659291 Neighboring gene AT-rich interaction domain 3C Neighboring gene ribonuclease P/MRP subunit p25 like Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene dynein axonemal intermediate chain 1 Neighboring gene energy homeostasis associated Neighboring gene small ribosomal subunit protein eS27-like Neighboring gene family with sequence similarity 219 member A Neighboring gene sperm microtubule inner protein 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Influence of maternal undernutrition and overfeeding on cardiac ciliary neurotrophic factor receptor and ventricular size in fetal sheep. Dong F, et al. J Nutr Biochem, 2008 Jun. PMID 17869083, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ciliary neurotrophic factor receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytokine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CNTFR-CLCF1 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ciliary neurotrophic factor receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ciliary neurotrophic factor receptor subunit alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      36976075..37039723
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_060410884.1 → XP_060266867.1  ciliary neurotrophic factor receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A6P7DN59, W5PHJ0

    2. XM_027964277.3 → XP_027820078.1  ciliary neurotrophic factor receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A6P7DN59, W5PHJ0
      Related
      ENSOARP00020008451.1, ENSOART00020010243.2

    3. XM_015093062.4 → XP_014948548.1  ciliary neurotrophic factor receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A6P7DN59, W5PHJ0
      Conserved Domains (3) summary
      smart00408
      Location:39 → 96
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:31 → 105
      IG_like; Immunoglobulin like
      cd00063
      Location:204 → 300
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    4. XM_015093061.4 → XP_014948547.1  ciliary neurotrophic factor receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A6P7DN59, W5PHJ0
      Conserved Domains (3) summary
      smart00408
      Location:39 → 96
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:31 → 105
      IG_like; Immunoglobulin like
      cd00063
      Location:204 → 300
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    5. XM_027964280.3 → XP_027820081.1  ciliary neurotrophic factor receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A6P7DN59, W5PHJ0

    6. XM_027964279.3 → XP_027820080.1  ciliary neurotrophic factor receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A6P7DN59, W5PHJ0

    7. XM_027964278.3 → XP_027820079.1  ciliary neurotrophic factor receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A6P7DN59, W5PHJ0

    8. XM_027964283.3 → XP_027820084.1  ciliary neurotrophic factor receptor subunit alpha isoform X2

      Related
      ENSOARP00020056394.1, ENSOART00020065192.1

    9. XM_027964282.3 → XP_027820083.1  ciliary neurotrophic factor receptor subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A6P7DN59, W5PHJ0
    Nucleotide Protein Strain
    Heading Accession and Version

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