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    FSHR follicle stimulating hormone receptor [ Capra hircus (goat) ]

    Gene ID: 100861291, updated on 8-Mar-2024

    Summary

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    Gene symbol
    FSHR
    Gene description
    follicle stimulating hormone receptor
    See related
    EnsemblRapid:ENSCHIG00000023353
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Capra hircus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
    Orthologs
    human mouse all
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    Genomic context

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    See FSHR in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    102 current ASM170441v1 (GCF_001704415.1) 11 NC_030818.1 (30824873..31014405, complement)
    101 previous assembly CHIR_1.0 (GCF_000317765.1) 11 NC_022303.1 (30728145..30917766, complement)

    Chromosome 11 - NC_030818.1Genomic Context describing neighboring genes Neighboring gene general transcription factor IIA subunit 1 like Neighboring gene luteinizing hormone/choriogonadotropin receptor Neighboring gene 60S ribosomal protein L21-like Neighboring gene 40S ribosomal protein S13 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Anti-Müllerian hormone reduces growth rate without altering follicular survival in isolated caprine preantral follicles cultured in vitro. Rocha RMP, et al. Reprod Fertil Dev, 2017 Jun. PMID 27166082
    2. The effects of insulin and follicle-simulating hormone (FSH) during in vitro development of ovarian goat preantral follicles and the relative mRNA expression for insulin and FSH receptors and cytochrome P450 aromatase in cultured follicles. Chaves RN, et al. Biol Reprod, 2012 Sep. PMID 22811569
    3. Cloning and expression levels of genes relating to the ovulation rate of the Yunling black goat. Cui HX, et al. Biol Reprod, 2009 Feb. PMID 18987334

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data suggest that signaling via AMH/AMH-receptor and/or FSH/FSH-receptor reduces follicular growth rate of pre-antral ovarian follicles without affecting follicular cell survival. These studies were conducted using in vitro tissue culture techniques. (AMH = anti-Mullerian hormone; FSH = follicle-stimulating hormone receptor)
      Title: Anti-Müllerian hormone reduces growth rate without altering follicular survival in isolated caprine preantral follicles cultured in vitro.
    2. Relative mRNA expression for insulin and FSH receptors and cytochrome P450 aromatase in cultured follicles.
      Title: The effects of insulin and follicle-simulating hormone (FSH) during in vitro development of ovarian goat preantral follicles and the relative mRNA expression for insulin and FSH receptors and cytochrome P450 aromatase in cultured follicles.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables follicle-stimulating hormone receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in follicle-stimulating hormone signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in male gonad development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    follicle-stimulating hormone receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001285636.1 → NP_001272565.1  follicle-stimulating hormone receptor precursor

      See identical proteins and their annotated locations for NP_001272565.1

      Status: PROVISIONAL

      Source sequence(s)
      EU847283
      UniProtKB/TrEMBL
      B5AFX4, B5AFX9
      Related
      ENSCHIP00000027733.2, ENSCHIT00000035601.2
      Conserved Domains (6) summary
      smart00013
      Location:17 → 50
      LRRNT; Leucine rich repeat N-terminal domain
      sd00033
      Location:72 → 96
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00001
      Location:379 → 626
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      pfam12369
      Location:282 → 349
      GnHR_trans; Gonadotropin hormone receptor transmembrane region
      pfam13306
      Location:61 → 216
      LRR_5; Leucine rich repeats (6 copies)
      pfam13855
      Location:193 → 245
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM170441v1 Primary Assembly

    Genomic

    1. NC_030818.1 Reference ASM170441v1 Primary Assembly

      Range
      30824873..31014405 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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