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    TNNI3 troponin I3, cardiac type [ Capra hircus (goat) ]

    Gene ID: 100860775, updated on 8-Mar-2024

    Summary

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    Gene symbol
    TNNI3
    Gene description
    troponin I3, cardiac type
    See related
    EnsemblRapid:ENSCHIG00000020498
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Capra hircus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
    Orthologs
    human mouse all
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    Genomic context

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    See TNNI3 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    102 current ASM170441v1 (GCF_001704415.1) 18 NC_030825.1 (64027068..64030942)
    101 previous assembly CHIR_1.0 (GCF_000317765.1) 18 NC_022310.1 (58404219..58406707)

    Chromosome 18 - NC_030825.1Genomic Context describing neighboring genes Neighboring gene synaptotagmin 5 Neighboring gene dynein axonemal assembly factor 3 Neighboring gene troponin T1, slow skeletal type Neighboring gene protein phosphatase 1 regulatory subunit 12C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cardiac biomarkers troponin I and CK-MB in nonpregnant and pregnant goats, goats with normal birth, goats with prolonged birth, and goats with pregnancy toxemia. Tharwat M, et al. Theriogenology, 2012 Oct 15. PMID 22980083
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Serum cardiac troponin I is elevated in goats with pregnancy toxemia, indicating some degree of cardiac dysfunction
      Title: The cardiac biomarkers troponin I and CK-MB in nonpregnant and pregnant goats, goats with normal birth, goats with prolonged birth, and goats with pregnancy toxemia.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of troponin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    troponin I, cardiac muscle

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001314239.1 → NP_001301168.1  troponin I, cardiac muscle

      Status: PROVISIONAL

      Source sequence(s)
      JN848969
      UniProtKB/TrEMBL
      A0A452FEC1, I6V1W5
      Related
      ENSCHIP00000022611.2, ENSCHIT00000030471.2
      Conserved Domains (2) summary
      pfam11636
      Location:10 → 33
      Troponin-I_N; Troponin I residues 1-32
      pfam00992
      Location:48 → 179
      Troponin; Troponin

    RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM170441v1 Primary Assembly

    Genomic

    1. NC_030825.1 Reference ASM170441v1 Primary Assembly

      Range
      64027068..64030942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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