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    KIF5B kinesin family member 5B [ Canis lupus familiaris (dog) ]

    Gene ID: 100855651, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KIF5Bprovided by VGNC
    Official Full Name
    kinesin family member 5Bprovided by VGNC
    Primary source
    VGNC:VGNC:42408
    See related
    Ensembl:ENSCAFG00845009863
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See KIF5B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (13072118..13117087)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (12323571..12368548)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (12676797..12721749)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (12512247..12557211)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (12403006..12447970)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene dnaJ homolog subfamily A member 1-like Neighboring gene uncharacterized LOC119869981 Neighboring gene phosphate carrier protein, mitochondrial-like Neighboring gene U6 spliceosomal RNA Neighboring gene Rho GTPase activating protein 12 Neighboring gene uncharacterized LOC111091363

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stable knockdown of Kif5b in MDCK cells leads to epithelial-mesenchymal transition. Cui J, et al. Biochem Biophys Res Commun, 2015 Jul 17-24. PMID 26002460
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kinesin-1 heavy chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      13072118..13117087
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038658193.1 → XP_038514121.1  kinesin-1 heavy chain isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXA2, A0A8C0Q0Q3, A0A8I3N413, A0A8I3NBU4
      Related
      ENSCAFP00845013657.1, ENSCAFT00845017547.1
      Conserved Domains (3) summary
      COG4372
      Location:713 → 918
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      TIGR02168
      Location:414 → 803
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd01369
      Location:6 → 325
      KISc_KHC_KIF5; Kinesin motor domain, kinesin heavy chain (KHC) or KIF5-like subgroup

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      12512247..12557211
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038469163.1 → XP_038325091.1  kinesin-1 heavy chain isoform X1

      Conserved Domains (3) summary
      COG4372
      Location:713 → 918
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      TIGR02168
      Location:414 → 803
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd01369
      Location:6 → 325
      KISc_KHC_KIF5; Kinesin motor domain, kinesin heavy chain (KHC) or KIF5-like subgroup

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      12403006..12447970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038594125.1 → XP_038450053.1  kinesin-1 heavy chain isoform X1

      Conserved Domains (3) summary
      COG4372
      Location:713 → 918
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      TIGR02168
      Location:414 → 803
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd01369
      Location:6 → 325
      KISc_KHC_KIF5; Kinesin motor domain, kinesin heavy chain (KHC) or KIF5-like subgroup

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      12676797..12721749
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038529873.1 → XP_038385801.1  kinesin-1 heavy chain isoform X2

      UniProtKB/TrEMBL
      A0A8C0Q0Q3, A0A8I3NBU4

    RNA

    1. XR_005355202.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      12323571..12368548
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003638878.5 → XP_003638926.1  kinesin-1 heavy chain isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXA2, A0A8C0Q0Q3, A0A8I3N413, A0A8I3NBU4
      Conserved Domains (3) summary
      COG4372
      Location:713 → 918
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
      TIGR02168
      Location:414 → 803
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd01369
      Location:6 → 325
      KISc_KHC_KIF5; Kinesin motor domain, kinesin heavy chain (KHC) or KIF5-like subgroup
    Nucleotide Protein
    Heading Accession and Version

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