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    LOC100767740 tyrosine-protein kinase ZAP-70 [ Cricetulus griseus (Chinese hamster) ]

    Gene ID: 100767740, updated on 11-Apr-2024

    Summary

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    Gene symbol
    LOC100767740
    Gene description
    tyrosine-protein kinase ZAP-70
    Locus tag
    I79_004087
    See related
    Ensembl:ENSCGRG00015014975
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cricetulus griseus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
    Also known as
    Zap70
    Orthologs
    human mouse all
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    Genomic context

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    See LOC100767740 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613687.1 (739914..747012, complement)
    104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276807.1 (11427209..11434257, complement)

    NW_003613687.1Genomic Context describing neighboring genes Neighboring gene von Willebrand factor A domain containing 3B Neighboring gene transmembrane protein 131 Neighboring gene chromosome unknown C2orf92 homolog Neighboring gene actin related protein 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extrinsic component of cytoplasmic side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase ZAP-70
    Names
    zeta-chain (TCR) associated protein kinase 70kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CriGri_1.0 Primary Assembly

    Genomic

    1. NW_003613687.1 Reference CriGri_1.0 Primary Assembly

      Range
      739914..747012 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035446054.1 → XP_035301945.1  tyrosine-protein kinase ZAP-70 isoform X3

      UniProtKB/TrEMBL
      A0A8C2QI47, G3H1Q5
      Conserved Domains (3) summary
      cd09938
      Location:8 → 111
      SH2_N-SH2_Zap70_Syk_like; N-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70) and Spleen tyrosine kinase (Syk) proteins
      cd05115
      Location:329 → 597
      PTKc_Zap-70; Catalytic domain of the Protein Tyrosine Kinase, Zeta-chain-associated protein of 70kDa
      cl15255
      Location:152 → 256
      SH2; Src homology 2 (SH2) domain

    2. XM_035446052.1 → XP_035301943.1  tyrosine-protein kinase ZAP-70 isoform X2

      UniProtKB/TrEMBL
      A0A9J7KEU5, G3H1Q5
      Conserved Domains (3) summary
      cd09938
      Location:8 → 111
      SH2_N-SH2_Zap70_Syk_like; N-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70) and Spleen tyrosine kinase (Syk) proteins
      cd05115
      Location:326 → 594
      PTKc_Zap-70; Catalytic domain of the Protein Tyrosine Kinase, Zeta-chain-associated protein of 70kDa
      cl15255
      Location:152 → 256
      SH2; Src homology 2 (SH2) domain

    3. XM_035446049.1 → XP_035301940.1  tyrosine-protein kinase ZAP-70 isoform X1

      UniProtKB/TrEMBL
      A0A9J7KFV4, G3H1Q5
      Conserved Domains (3) summary
      cd09938
      Location:8 → 111
      SH2_N-SH2_Zap70_Syk_like; N-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70) and Spleen tyrosine kinase (Syk) proteins
      cd05115
      Location:334 → 602
      PTKc_Zap-70; Catalytic domain of the Protein Tyrosine Kinase, Zeta-chain-associated protein of 70kDa
      cl15255
      Location:152 → 256
      SH2; Src homology 2 (SH2) domain

    Alternate CriGri-PICRH-1.0

    Genomic

    1. NW_023276807.1 Alternate CriGri-PICRH-1.0

      Range
      11427209..11434257 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035453440.1 → XP_035309331.1  tyrosine-protein kinase ZAP-70 isoform X3

      UniProtKB/TrEMBL
      A0A8C2QI47, G3H1Q5
      Related
      ENSCGRP00015019572.2, ENSCGRT00015024129.2
      Conserved Domains (3) summary
      cd09938
      Location:8 → 111
      SH2_N-SH2_Zap70_Syk_like; N-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70) and Spleen tyrosine kinase (Syk) proteins
      cd05115
      Location:329 → 597
      PTKc_Zap-70; Catalytic domain of the Protein Tyrosine Kinase, Zeta-chain-associated protein of 70kDa
      cl15255
      Location:152 → 256
      SH2; Src homology 2 (SH2) domain

    2. XM_035453439.1 → XP_035309330.1  tyrosine-protein kinase ZAP-70 isoform X2

      UniProtKB/TrEMBL
      A0A9J7KEU5, G3H1Q5
      Conserved Domains (3) summary
      cd09938
      Location:8 → 111
      SH2_N-SH2_Zap70_Syk_like; N-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70) and Spleen tyrosine kinase (Syk) proteins
      cd05115
      Location:326 → 594
      PTKc_Zap-70; Catalytic domain of the Protein Tyrosine Kinase, Zeta-chain-associated protein of 70kDa
      cl15255
      Location:152 → 256
      SH2; Src homology 2 (SH2) domain

    3. XM_035453438.1 → XP_035309329.1  tyrosine-protein kinase ZAP-70 isoform X1

      UniProtKB/TrEMBL
      A0A9J7KFV4, G3H1Q5
      Conserved Domains (3) summary
      cd09938
      Location:8 → 111
      SH2_N-SH2_Zap70_Syk_like; N-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70) and Spleen tyrosine kinase (Syk) proteins
      cd05115
      Location:334 → 602
      PTKc_Zap-70; Catalytic domain of the Protein Tyrosine Kinase, Zeta-chain-associated protein of 70kDa
      cl15255
      Location:152 → 256
      SH2; Src homology 2 (SH2) domain
    Nucleotide Protein Strain
    Heading Accession and Version

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