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    Smo smoothened, frizzled class receptor [ Cricetulus griseus (Chinese hamster) ]

    Gene ID: 100762005, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Smo
    Gene description
    smoothened, frizzled class receptor
    See related
    Ensembl:ENSCGRG00015026286
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cricetulus griseus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See Smo in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613652.1 (1894997..1920517)
    104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (198071094..198097432, complement)

    NW_003613652.1Genomic Context describing neighboring genes Neighboring gene transportin 3 Neighboring gene obg-like ATPase 1 Neighboring gene tetraspanin 33 Neighboring gene 60S ribosomal protein L31-like Neighboring gene adenosylhomocysteinase like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables patched binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in central nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in commissural neuron axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    smoothened homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CriGri_1.0 Primary Assembly

    Genomic

    1. NW_003613652.1 Reference CriGri_1.0 Primary Assembly

      Range
      1894997..1920517
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027395298.2 → XP_027251099.2  smoothened homolog isoform X1

      UniProtKB/TrEMBL
      A0A061IJT9, A0A8C2MHN2
      Conserved Domains (2) summary
      cd07451
      Location:72 → 202
      CRD_SMO; Cysteine-rich domain of the smoothened receptor (Smo) integral membrane protein
      cd15030
      Location:226 → 556
      7tmF_SMO_homolog; class F smoothened family membrane region, a homolog of frizzled receptors

    Alternate CriGri-PICRH-1.0

    Genomic

    1. NW_023276806.1 Alternate CriGri-PICRH-1.0

      Range
      198071094..198097432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027391371.2 → XP_027247172.1  smoothened homolog isoform X2

      UniProtKB/TrEMBL
      A0A061IJT9, A0A8C2MHN2
      Related
      ENSCGRP00015034984.2, ENSCGRT00015042634.2
      Conserved Domains (2) summary
      cd07451
      Location:72 → 202
      CRD_SMO; Cysteine-rich domain of the smoothened receptor (Smo) integral membrane protein
      cd15030
      Location:226 → 556
      7tmF_SMO_homolog; class F smoothened family membrane region, a homolog of frizzled receptors
    Nucleotide Protein Strain
    Heading Accession and Version

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