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    Git1 GIT ArfGAP 1 [ Cricetulus griseus (Chinese hamster) ]

    Gene ID: 100758194, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Git1
    Gene description
    GIT ArfGAP 1
    Locus tag
    I79_013368
    See related
    Ensembl:ENSCGRG00015016835
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cricetulus griseus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See Git1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614210.1 (946187..954923)
    104 current CriGri-PICRH-1.0 (GCF_003668045.3) 7 NC_048600.1 (90897151..90911201)

    NW_003614210.1Genomic Context describing neighboring genes Neighboring gene slingshot protein phosphatase 2 Neighboring gene 40S ribosomal protein S26-like Neighboring gene ankyrin repeat domain 13B Neighboring gene coronin 6 Neighboring gene 40S ribosomal protein S27-like Neighboring gene tumor protein p53 inducible protein 13 Neighboring gene abhydrolase domain containing 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ARF GTPase-activating protein GIT1
    Names
    G protein-coupled receptor kinase interacting ArfGAP 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CriGri_1.0 Primary Assembly

    Genomic

    1. NW_003614210.1 Reference CriGri_1.0 Primary Assembly

      Range
      946187..954923
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035458111.1 → XP_035314002.1  ARF GTPase-activating protein GIT1 isoform X1

      UniProtKB/TrEMBL
      A0A8C2MHZ7, A0A8C2MJ29
      Conserved Domains (6) summary
      sd00045
      Location:137 → 165
      ANK; ANK repeat [structural motif]
      cd08846
      Location:1 → 111
      ArfGap_GIT1; GIT1 GTPase activating protein for Arf
      pfam08518
      Location:328 → 356
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:638 → 754
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137 → 229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:409 → 474
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor

    Alternate CriGri-PICRH-1.0

    Genomic

    1. NC_048600.1 Alternate CriGri-PICRH-1.0

      Range
      90897151..90911201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027426658.2 → XP_027282459.1  ARF GTPase-activating protein GIT1 isoform X4

      UniProtKB/TrEMBL
      A0A8C2MHZ7, A0A8C2MJ29
      Related
      ENSCGRP00015022277.2, ENSCGRT00015027338.2
      Conserved Domains (6) summary
      sd00045
      Location:137 → 165
      ANK; ANK repeat [structural motif]
      cd08846
      Location:1 → 111
      ArfGap_GIT1; GIT1 GTPase activating protein for Arf
      pfam08518
      Location:328 → 356
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:638 → 754
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137 → 229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:409 → 474
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor

    2. XM_035447348.1 → XP_035303239.1  ARF GTPase-activating protein GIT1 isoform X2

      UniProtKB/TrEMBL
      A0A8C2MJ29, A0A9J7H5F4
      Related
      ENSCGRP00015022217.2, ENSCGRT00015027267.2
      Conserved Domains (6) summary
      sd00045
      Location:161 → 189
      ANK; ANK repeat [structural motif]
      cl28907
      Location:42 → 135
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      pfam08518
      Location:352 → 380
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:662 → 778
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:161 → 253
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:433 → 498
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor

    3. XM_035447349.1 → XP_035303240.1  ARF GTPase-activating protein GIT1 isoform X3

      UniProtKB/TrEMBL
      A0A8C2MJ29, A0A9J7KBA6
      Conserved Domains (6) summary
      sd00045
      Location:161 → 189
      ANK; ANK repeat [structural motif]
      cl28907
      Location:42 → 135
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      pfam08518
      Location:352 → 380
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:657 → 773
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:161 → 253
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:433 → 493
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    Nucleotide Protein Strain
    Heading Accession and Version

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