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    Rad50 RAD50 double strand break repair protein [ Cricetulus griseus (Chinese hamster) ]

    Gene ID: 100755349, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Rad50
    Gene description
    RAD50 double strand break repair protein
    Locus tag
    I79_004318
    See related
    Ensembl:ENSCGRG00015024005
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cricetulus griseus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See Rad50 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613693.1 (34848..93826)
    104 current CriGri-PICRH-1.0 (GCF_003668045.3) 7 NC_048600.1 (67795764..67857014, complement)

    NW_003613693.1Genomic Context describing neighboring genes Neighboring gene interleukin 5 Neighboring gene interleukin 13 Neighboring gene interleukin 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables G-quadruplex DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chromosome organization involved in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere maintenance via recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere maintenance via telomerase IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Mre11 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in condensed nuclear chromosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA repair protein RAD50
    Names
    RAD50 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CriGri_1.0 Primary Assembly

    Genomic

    1. NW_003613693.1 Reference CriGri_1.0 Primary Assembly

      Range
      34848..93826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003498479.4 → XP_003498527.2  DNA repair protein RAD50 isoform X1

      UniProtKB/TrEMBL
      A0A8C2LI41
      Conserved Domains (3) summary
      TIGR00606
      Location:2 → 1300
      rad50; rad50
      cd03240
      Location:1195 → 1297
      ABC_Rad50; ATP-binding cassette domain of Rad50
      pfam04423
      Location:661 → 709
      Rad50_zn_hook; Rad50 zinc hook motif

    Alternate CriGri-PICRH-1.0

    Genomic

    1. NC_048600.1 Alternate CriGri-PICRH-1.0

      Range
      67795764..67857014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027427526.2 → XP_027283327.1  DNA repair protein RAD50 isoform X2

      UniProtKB/TrEMBL
      A0A8C2LI41, A0A9J7GEE0
      Related
      ENSCGRP00015031857.1, ENSCGRT00015038898.2
    Nucleotide Protein Strain
    Heading Accession and Version

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