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    Celsr2 cadherin EGF LAG seven-pass G-type receptor 2 [ Cricetulus griseus (Chinese hamster) ]

    Gene ID: 100751011, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Celsr2
    Gene description
    cadherin EGF LAG seven-pass G-type receptor 2
    Locus tag
    I79_019398
    See related
    Ensembl:ENSCGRG00015026493
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cricetulus griseus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
    Orthologs
    human mouse all
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    Genomic context

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    See Celsr2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614997.1 (361929..396063, complement)
    104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (48699640..48723774)

    NW_003614997.1Genomic Context describing neighboring genes Neighboring gene myosin binding protein H like Neighboring gene proline and serine rich coiled-coil 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: cadherin EGF LAG seven-pass G-type receptor 2; cadherin EGF LAG seven-pass G-type receptor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CriGri_1.0 Primary Assembly

    Genomic

    1. NW_003614997.1 Reference CriGri_1.0 Primary Assembly

      Range
      361929..396063 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035461529.1 → XP_035317420.1  LOW QUALITY PROTEIN: cadherin EGF LAG seven-pass G-type receptor 2 isoform X1

      UniProtKB/TrEMBL
      A0A061ILG8
      Conserved Domains (11) summary
      smart00303
      Location:2340 → 2393
      GPS; G-protein-coupled receptor proteolytic site domain
      cd11304
      Location:430 → 527
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00008
      Location:1997 → 2059
      HormR; Domain present in hormone receptors
      smart00180
      Location:1949 → 1994
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      cd00054
      Location:1314 → 1349
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:1394 → 1577
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam01500
      Location:1831 → 1981
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam00008
      Location:1603 → 1632
      EGF; EGF-like domain
      pfam16489
      Location:2076 → 2314
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:2400 → 2425
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:2398 → 2651
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    Alternate CriGri-PICRH-1.0

    Genomic

    1. NW_023276806.1 Alternate CriGri-PICRH-1.0

      Range
      48699640..48723774
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027395501.2 → XP_027251302.1  cadherin EGF LAG seven-pass G-type receptor 2 isoform X2

      UniProtKB/TrEMBL
      A0A061ILG8, A0A8C2MP33
      Related
      ENSCGRP00015035307.1, ENSCGRT00015043020.2
    Nucleotide Protein Strain
    Heading Accession and Version

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