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    ADAD2 adenosine deaminase domain containing 2 [ Sus scrofa (pig) ]

    Gene ID: 100737909, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAD2provided by VGNC
    Official Full Name
    adenosine deaminase domain containing 2provided by VGNC
    Primary source
    VGNC:VGNC:85059
    See related
    Ensembl:ENSSSCG00000034385
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Restricted expression toward ovary (RPKM 16.2) See more
    Orthologs
    human mouse all
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    Genomic context

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    See ADAD2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (4437797..4444068, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (4862053..4868711, complement)

    Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110260899 Neighboring gene potassium voltage-gated channel modifier subfamily G member 4 Neighboring gene uncharacterized LOC102165143 Neighboring gene TATA-box binding protein associated factor, RNA polymerase I subunit C Neighboring gene uncharacterized LOC110260901 Neighboring gene dynein axonemal assembly factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables double-stranded RNA adenosine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tRNA-specific adenosine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenosine to inosine editing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenosine deaminase domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

      Range
      4437797..4444068 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021093734.1 → XP_020949393.1  adenosine deaminase domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A480DL75
      Conserved Domains (1) summary
      pfam02137
      Location:195 → 510
      A_deamin; Adenosine-deaminase (editase) domain

    2. XM_013988486.2 → XP_013843940.1  adenosine deaminase domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A480DL75
      Related
      ENSSSCP00000002885.5, ENSSSCT00000002964.5
      Conserved Domains (2) summary
      cd00048
      Location:97 → 160
      DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
      pfam02137
      Location:242 → 557
      A_deamin; Adenosine-deaminase (editase) domain
    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials