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    Kcnn2 potassium calcium-activated channel subfamily N member 2 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100734732, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Kcnn2
    Gene description
    potassium calcium-activated channel subfamily N member 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Also known as
    Sk2
    Orthologs
    human mouse all
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    Genomic context

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    See Kcnn2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947502.1 (35709083..36185606)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176402.1 (27925431..28085700)

    NW_026947502.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134471637 Neighboring gene uncharacterized LOC134471638 Neighboring gene uncharacterized LOC111757810 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional interactions between the SK2 channel and the nicotinic acetylcholine receptor in enteric neurons of the guinea pig ileum. Nakajima H, et al. J Neurochem, 2007 Dec. PMID 17953675
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small conductance calcium-activated potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small conductance calcium-activated potassium channel protein 2
    Names
    potassium intermediate/small conductance calcium-activated channel type2
    potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947502.1 Reference mCavPor4.1

      Range
      35709083..36185606
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063230941.1 → XP_063087011.1  small conductance calcium-activated potassium channel protein 2 isoform X1

    2. XM_063230944.1 → XP_063087014.1  small conductance calcium-activated potassium channel protein 2 isoform X1

    3. XM_063230942.1 → XP_063087012.1  small conductance calcium-activated potassium channel protein 2 isoform X1

    4. XM_063230945.1 → XP_063087015.1  small conductance calcium-activated potassium channel protein 2 isoform X1

    5. XM_013156196.3 → XP_013011650.1  small conductance calcium-activated potassium channel protein 2 isoform X2

      Conserved Domains (3) summary
      smart01053
      Location:216 → 291
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:1 → 35
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:123 → 202
      Ion_trans_2; Ion channel

    6. XM_063230947.1 → XP_063087017.1  small conductance calcium-activated potassium channel protein 2 isoform X2

    7. XM_063230948.1 → XP_063087018.1  small conductance calcium-activated potassium channel protein 2 isoform X2

    8. XM_063230946.1 → XP_063087016.1  small conductance calcium-activated potassium channel protein 2 isoform X1

    9. XM_063230943.1 → XP_063087013.1  small conductance calcium-activated potassium channel protein 2 isoform X1

    Nucleotide Protein
    Heading Accession and Version

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