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    Spry1 sprouty RTK signaling antagonist 1 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100734287, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Spry1
    Gene description
    sprouty RTK signaling antagonist 1
    See related
    Ensembl:ENSCPOG00000035769
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    See Spry1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947497.1 (20845537..20852257)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176412.1 (4919634..4926831)

    NW_026947497.1Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor 2 Neighboring gene nudix hydrolase 6 Neighboring gene AFG2 AAA ATPase homolog A Neighboring gene uncharacterized LOC111753592 Neighboring gene uncharacterized LOC134478678 Neighboring gene E3 ubiquitin-protein ligase RNF138-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of fibroblast growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein sprouty homolog 1
    Names
    sprouty homolog 1, antagonist of FGF signaling

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947497.1 Reference mCavPor4.1

      Range
      20845537..20852257
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013160376.3 → XP_013015830.1  protein sprouty homolog 1 isoform X3

      See identical proteins and their annotated locations for XP_013015830.1

      UniProtKB/TrEMBL
      A0A286Y5D7
      Conserved Domains (1) summary
      pfam05210
      Location:187 → 284
      Sprouty; Sprouty protein (Spry)

    2. XM_005006772.4 → XP_005006829.1  protein sprouty homolog 1 isoform X3

      See identical proteins and their annotated locations for XP_005006829.1

      UniProtKB/TrEMBL
      A0A286Y5D7
      Conserved Domains (1) summary
      pfam05210
      Location:187 → 284
      Sprouty; Sprouty protein (Spry)

    3. XM_005006771.4 → XP_005006828.1  protein sprouty homolog 1 isoform X3

      See identical proteins and their annotated locations for XP_005006828.1

      UniProtKB/TrEMBL
      A0A286Y5D7
      Related
      ENSCPOP00000032785.1
      Conserved Domains (1) summary
      pfam05210
      Location:187 → 284
      Sprouty; Sprouty protein (Spry)

    4. XM_063260747.1 → XP_063116817.1  protein sprouty homolog 1 isoform X2

    5. XM_013160375.3 → XP_013015829.1  protein sprouty homolog 1 isoform X1

      Conserved Domains (1) summary
      pfam05210
      Location:234 → 331
      Sprouty; Sprouty protein (Spry)
    Nucleotide Protein
    Heading Accession and Version

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