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    Grik2 glutamate ionotropic receptor kainate type subunit 2 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100733104, updated on 10-Oct-2024

    Summary

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    Gene symbol
    Grik2
    Gene description
    glutamate ionotropic receptor kainate type subunit 2
    See related
    Ensembl:ENSCPOG00000001674
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    See Grik2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947490.1 (90066171..90678120)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176356.1 (1691805..2305971)

    NW_026947490.1Genomic Context describing neighboring genes Neighboring gene SIM bHLH transcription factor 1 Neighboring gene activating signal cointegrator 1 complex subunit 3 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134476770

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kainate selective glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in modulation of chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of kainate selective glutamate receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate receptor ionotropic, kainate 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947490.1 Reference mCavPor4.1

      Range
      90066171..90678120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063253933.1 → XP_063110003.1  glutamate receptor ionotropic, kainate 2 isoform X1

      UniProtKB/TrEMBL
      H0UWR5

    2. XM_013148503.3 → XP_013003957.1  glutamate receptor ionotropic, kainate 2 isoform X2

      UniProtKB/TrEMBL
      A0A286X8R3
      Related
      ENSCPOP00000024446.1
      Conserved Domains (4) summary
      pfam00060
      Location:562 → 831
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:52 → 395
      ANF_receptor; Receptor family ligand binding region
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    3. XM_063253934.1 → XP_063110004.1  glutamate receptor ionotropic, kainate 2 isoform X4

      UniProtKB/TrEMBL
      A0A286XGF6

    4. XM_003466022.5 → XP_003466070.1  glutamate receptor ionotropic, kainate 2 isoform X1

      UniProtKB/TrEMBL
      A0A286X8R3, H0UWR5
      Related
      ENSCPOP00000001510.3
      Conserved Domains (2) summary
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 800
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    5. XM_023563450.2 → XP_023419218.1  glutamate receptor ionotropic, kainate 2 isoform X3

      UniProtKB/TrEMBL
      A0A286X8R3
      Conserved Domains (2) summary
      cl10011
      Location:34 → 414
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
      cl21456
      Location:430 → 762
      Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

    6. XM_063253935.1 → XP_063110005.1  glutamate receptor ionotropic, kainate 2 isoform X5

      UniProtKB/TrEMBL
      A0A286XNX5
    Nucleotide Protein
    Heading Accession and Version

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