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    Pparg peroxisome proliferator activated receptor gamma [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100729138, updated on 10-Oct-2024

    Summary

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    Gene symbol
    Pparg
    Gene description
    peroxisome proliferator activated receptor gamma
    See related
    Ensembl:ENSCPOG00000002043
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    See Pparg in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947510.1 (19292444..19436795, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176296.1 (2246966..2363177, complement)

    NW_026947510.1Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase greatwall-like Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene tRNA splicing endonuclease subunit 2 Neighboring gene synapsin II Neighboring gene TIMP metallopeptidase inhibitor 4 Neighboring gene small nuclear ribonucleoprotein-associated protein B-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hormone-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cholesterol storage IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxisome proliferator-activated receptor gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947510.1 Reference mCavPor4.1

      Range
      19292444..19436795 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063237987.1 → XP_063094057.1  peroxisome proliferator-activated receptor gamma isoform X1

      UniProtKB/TrEMBL
      H0VXF9

    2. XM_063237985.1 → XP_063094055.1  peroxisome proliferator-activated receptor gamma isoform X1

      UniProtKB/TrEMBL
      H0VXF9

    3. XM_063237983.1 → XP_063094053.1  peroxisome proliferator-activated receptor gamma isoform X1

      UniProtKB/TrEMBL
      H0VXF9

    4. XM_003462736.5 → XP_003462784.2  peroxisome proliferator-activated receptor gamma isoform X1

      See identical proteins and their annotated locations for XP_003462784.2

      UniProtKB/TrEMBL
      H0VXF9, Q99PC7
      Related
      ENSCPOP00000015389.2
      Conserved Domains (3) summary
      cd06932
      Location:207 → 474
      NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
      cd06965
      Location:108 → 191
      NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
      pfam12577
      Location:1 → 78
      PPARgamma_N; PPAR gamma N-terminal region

    5. XM_013144496.3 → XP_012999950.1  peroxisome proliferator-activated receptor gamma isoform X1

      See identical proteins and their annotated locations for XP_012999950.1

      UniProtKB/TrEMBL
      H0VXF9, Q99PC7
      Conserved Domains (3) summary
      cd06932
      Location:207 → 474
      NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
      cd06965
      Location:108 → 191
      NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
      pfam12577
      Location:1 → 78
      PPARgamma_N; PPAR gamma N-terminal region

    6. XM_013144495.3 → XP_012999949.1  peroxisome proliferator-activated receptor gamma isoform X1

      See identical proteins and their annotated locations for XP_012999949.1

      UniProtKB/TrEMBL
      H0VXF9, Q99PC7
      Conserved Domains (3) summary
      cd06932
      Location:207 → 474
      NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
      cd06965
      Location:108 → 191
      NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
      pfam12577
      Location:1 → 78
      PPARgamma_N; PPAR gamma N-terminal region

    7. XM_063237986.1 → XP_063094056.1  peroxisome proliferator-activated receptor gamma isoform X1

      UniProtKB/TrEMBL
      H0VXF9

    8. XM_063237984.1 → XP_063094054.1  peroxisome proliferator-activated receptor gamma isoform X1

      UniProtKB/TrEMBL
      H0VXF9

    9. XM_023561919.2 → XP_023417687.1  peroxisome proliferator-activated receptor gamma isoform X2

      Conserved Domains (1) summary
      cd06932
      Location:34 → 265
      NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors

    RNA

    1. XR_010043763.1 RNA Sequence

    2. XR_010043764.1 RNA Sequence

    3. XR_010043762.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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