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    Tnks tankyrase [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100728577, updated on 18-Sep-2024

    Summary

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    Gene symbol
    Tnks
    Gene description
    tankyrase
    See related
    Ensembl:ENSCPOG00000010040
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    See Tnks in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947507.1 (1413251..1584738, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176289.1 (1384908..1557495, complement)

    NW_026947507.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134472638 Neighboring gene dual specificity phosphatase 4 Neighboring gene uncharacterized LOC134472639 Neighboring gene small nucleolar RNA SNORA2/SNORA34 family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD+-protein poly-ADP-ribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    poly [ADP-ribose] polymerase tankyrase-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947507.1 Reference mCavPor4.1

      Range
      1413251..1584738 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003462614.5 → XP_003462662.1  poly [ADP-ribose] polymerase tankyrase-1

      UniProtKB/TrEMBL
      A0A286XUG8, H0VFZ7
      Related
      ENSCPOP00000029182.1
      Conserved Domains (8) summary
      cd09524
      Location:1024 → 1089
      SAM_tankyrase1,2; SAM domain of tankyrase1,2 subfamily
      smart00454
      Location:1030 → 1087
      SAM; Sterile alpha motif
      cd00204
      Location:676 → 801
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01438
      Location:1091 → 1313
      tankyrase_like; Tankyrases interact with the telomere reverse transcriptase complex (TERT). Tankyrase 1 poly-ADP-ribosylates Telomere Repeat Binding Factor 1 (TRF1) while Tankyrase 2 can poly-ADP-ribosylate itself or TRF1. The tankyrases also contain multiple ankyrin ...
      pfam00644
      Location:1105 → 1308
      PARP; Poly(ADP-ribose) polymerase catalytic domain
      pfam12796
      Location:688 → 780
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:803 → 857
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:371 → 399
      ANK; ANK repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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