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    LOC100721851 2'-5'-oligoadenylate synthase 1 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100721851, updated on 29-Feb-2024

    Summary

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    Gene symbol
    LOC100721851
    Gene description
    2'-5'-oligoadenylate synthase 1
    See related
    Ensembl:ENSCPOG00000037062
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Also known as
    Oas1
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    Genomic context

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    See LOC100721851 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947499.1 (10560786..10565948)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176304.1 (3948529..3953695)

    NW_026947499.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134470630 Neighboring gene uncharacterized LOC134470631 Neighboring gene U2 spliceosomal RNA Neighboring gene rabphilin 3A Neighboring gene 2'-5'-oligoadenylate synthase 3 Neighboring gene uncharacterized LOC134470633 Neighboring gene uncharacterized LOC134470634 Neighboring gene 2'-5'-oligoadenylate synthetase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2'-5'-oligoadenylate synthetase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of viral genome replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    2'-5'-oligoadenylate synthase 1
    Names
    2'-5'-oligoadenylate synthetase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947499.1 Reference mCavPor4.1

      Range
      10560786..10565948
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003462988.5 → XP_003463036.2  2'-5'-oligoadenylate synthase 1

      UniProtKB/TrEMBL
      A0A286X8S4
      Related
      ENSCPOP00000021818.1
      Conserved Domains (2) summary
      cd05400
      Location:29 → 218
      NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
      pfam10421
      Location:170 → 351
      OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
    Nucleotide Protein
    Heading Accession and Version

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